Knee Osteoarthritis
Conditions
Brief summary
80 patients diagnosed with knee osteoarthritis were randomized into two groups: patients in Group 1 received a single intraarticular injection of PRP whereas those in group 2 were administered three intraarticular injections of PRP within an interval of 2 weeks between each application. Patients were evaluated before the treatment and at the 6 month after the treatment with a Visual Analog Scale (VAS) and The Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index.
Interventions
OTHERprp injection
intraarticular prp
Sponsors
Izmir Democracy University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
35 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* ages of 35 and 80 * Kellgren-Lawrence grade of 2, 3, or 4
Exclusion criteria
* rheumatic diseases, coagulopathies, severe cardiovascular diseases, local infections, malignancies, immunodeficiency, schizophrenia, mental retardation, anticoagulant therapy, a hemoglobin concentration of 11 g/dL and platelets of 150,000/L, a history of severe trauma, or a history of hyaluronic acid or corticosteroid injection within the previous 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Western Ontario and MacMaster Universities (WOMAC) Osteoarthritis Index | baseline and 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS) | baseline and 6 months |
Countries
Turkey (Türkiye)
Outcome results
None listed