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Monitoring of Non-Surgical Treatment of Peri-implantitis

Monitoring of Non-Surgical Treatment of Peri-implantitis, Traditional Measurement Methods and aMMP-8 Test Technology-Cross Sectional Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06408467
Enrollment
40
Registered
2024-05-10
Start date
2022-01-01
Completion date
2022-11-15
Last updated
2024-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-Implantitis, Peri-implant Mucositis

Keywords

peri-implant treatment, aMMP-8, non-surgical treatment

Brief summary

This study aimed to investigate the response to non-surgical treatment of peri-implantitis diseases during the maintenance phase. The patients underwent non-surgical implant maintenance treatment, and the success of the treatment was measured again after 30 days using the same criteria and methods.

Detailed description

For 40 patients, the aMMP-8 test was performed on the buccal gingival pocket of the implant teeth, gingival bleeding (BOP), implant pocket depth (PPD), and a periapical x-ray to measure radiologic bone level (RBL) were taken.

Interventions

OTHERaMMP-8 diagnostic test

40 patients

Sponsors

University of Helsinki
CollaboratorOTHER
Lahanna oy
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
25 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* implant patients arriving for a maintenance visit at a dental clinic * a diagnosis of peri-implant healthy, peri-implant mucositis, or peri-implantitis by a dentist * a written informed consent.

Exclusion criteria

* Smoking * age under 25 * antibiotic treatment within six months * the maintenance treatment had been completed within 6 months.

Design outcomes

Primary

MeasureTime frameDescription
the result of the participants who were measured aMMP-81 monthMeasure aMMP-8-level ng/ml
the result of the participants who were measured BOP1 monthmeasure bleeding on probing in PISF
the result of the participants who were measured PPD1 monthmeasure peri-implant pocket depth

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026