Obsessive-Compulsive Disorder
Conditions
Keywords
children, adolescents, exposure with response prevention, cognitive behavioral therapy, ERP, CBT
Brief summary
The primary purpose of this study is to learn whether personalized assessment of obsessive-compulsive disorder (OCD) symptoms in childhood OCD using mobile health technology are feasible and acceptable for youth and parents. The investigators will also examine whether personalized cognitive-behavioral therapy (CBT) that is informed by personalized OCD assessments yields better clinical outcomes when compared to standard CBT for youth with OCD
Interventions
OTHERPersonalized Assessments
Personalized CBT will use individualized OCD symptom networks to guide CBT strategies to target central symptom nodes in contemporaneous networks.
OTHERStandard of Care
The standard CBT condition will use standard-of-care approaches to guide CBT strategies to target OCD symptoms.
Sponsors
Johns Hopkins University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Randomized parallel clinical trial
Eligibility
Sex/Gender
ALL
Age
8 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
1. be 8-17 years of age; 2. meet diagnostic criteria for a primary diagnosis of OCD on a structured clinical interview; 3. have moderate OCD severity as evidenced by a CY-BOCS total score of ≥16; 4. medication free and/or on a stable dose of medication 8 weeks prior to study participation; 5. be English speaking.
Exclusion criteria
1. the presence of psychotic disorder, bipolar disorder, or autism spectrum disorders; 2. significant suicidal ideation that warrants medical intervention; 3. concurrent psychotherapy for OCD; 4. inability to complete scales, or attend visits.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Children's Yale-Brown Obsessive-Compulsive Scale Second Edition (CY-BOCS-II) Total Severity Score | Screen, Baseline (Week 0), Week 4, Week 8, and Week 12 | A clinician-rated measure of OCD symptom severity in the past week. This 10-item measure is rated on a 0 to 5 scale with a total score ranging from 0 to 50. A higher total score is reflective of greater OCD symptom severity. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORJoseph F. McGuire, PhD
Johns Hopkins University
Outcome results
None listed