Iron Deficiency Anemia, Newborn; Vitality
Conditions
Keywords
Delayed cord clamping, hypothermia, polycythemia, iron deficiency anemia
Brief summary
After birth, the umbilical cord is usually clamped and separated from the placenta within the first 30 seconds. Although the exact time to clamp the umbilical cord is unknown, allowing placental transfusion after birth has many benefits for the newborn. Increased bleeding control, which is reported as a maternal complication, has not been found in studies. Approximately 28ml/kg additional blood volume is transferred to the baby with placental transfusion. The hemodynamics of the newborn are positively affected as the blood volume increases the right ventricular volume and the pulmonary pressure begins to decrease with the first breath. In addition, due to this additional blood volume, stem cells and erythrocytes pass through more. There are studies showing that it reduces iron deficiency that occurs in infants at the 4th month. In our study, we aimed to examine the effect of allowing placental transfusion until cord pulsation stopped and the effect of delayed cord clamping on iron deficiency at the 4th month in babies.
Detailed description
Healthy term newborns who will be born in our gynecology clinic; type of birth, week of gestation, birth weight, cord clamping time, cord blood gas, APGAR score, complete blood count, maternal complete blood count, maternal complications, baby's first body temperature, postnatal day 3 hematocrit and bilirubin level, diet, phototherapy treatment application Measurements will be determined and evaluated in terms of the baby's condition, monthly routine baby follow-up (anthropometric measurements and physical examination), and routine 4th month iron deficiency screening. These measurements and applications will be made by the baby nurse, pediatric assistant and pediatrician who will be present during the birth.
Interventions
PROCEDUREdelayed cord clamping (> 60 sec)
In the DCC group, cord pulse was checked without allowing clamping. Waited until the cord pulse stopped. It was wrapped in a sterile and warm cloth and dried. The cord was clamped when the pulse stopped. The cord clamping time was noted on the case report form. In DCC, the baby was placed on the mother's legs in cesarean section (C/S) births and on the mother's mons pubis region in normal vaginal births. The baby was administered a routine delivery room neonatal resuscitation program (NRP) by the pediatrician. After cord clamping, the baby was handed over to the pediatric team.
Sponsors
Goztepe Prof Dr Suleyman Yalcın City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
This was a single-center, with block randomisation \[1:1\], open-label, parallel group study.
Eligibility
Sex/Gender
ALL
Age
1 Days to 4 Months
Healthy volunteers
Yes
Inclusion criteria
* The healthy babies of healthy mothers (no pre-eclampsia, no diabetes, no prolonged rupture of membranes or signs of infection) term (gestational age ≥ 37 weeks) and no additional abnormality were included in the study.
Exclusion criteria
* . Babies who needed resuscitation were excluded from the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Iron deficiency anemia | 4 months | In terms of iron deficiency anemia, hb \< 11 g/dl and transferrin saturation \< 15% criteria were taken as basis |
| Polycythemia and indirect hyperbilirubinemia | 4 months | Polycythemia was defined by venous hematocrit above 65%. Hyperbilirubinemia was defined as the nomogram being above the phototherapy threshold value. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postpartum hemorrhage | 7 days | Postpartum bleeding greater than 500 ml |
Countries
Turkey (Türkiye)
Outcome results
None listed