Factors Affecting Abdominal Compliance During CO2 Insufflation in Laparoscopic Abdominal Surgery

Factors Influencing Abdominal Compliance During CO2 Insufflation in Patients Undergoing Laparoscopic Abdominal Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06396351

Enrollment

Registered

2024-05-02

Start date

2022-08-01

Completion date

2022-11-30

Last updated

2024-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic Surgery

Keywords

abdominal compliance, intraabdominal pressure, laparoscopic surgery

Brief summary

The authors aimed to evaluate factors influencing abdominal compliance in laparoscopic abdominal surgery.

Detailed description

During laparoscopic surgery, pneumoperitoneum is achieved by insufflating carbon dioxide (CO2) gas into the abdominal cavity to create a safe working space. Pneumoperitoneum-induced elevation in intra-abdominal pressure (IAP) can result in various complications. Abdominal compliance (AC), represents the slope of the P-V curve of the abdominal cavity and is a measure of the ease of abdominal dilatation, is important to balance between surgical safety and complications. The aim of this study was to determine the effect of demographic and anatomic variables on AC. The study included 90 patients who underwent laparoscopic abdominal surgery. Subcutaneous adipose tissue and abdominal muscle thickness were measured ultrasonographically. Mean AC was calculated during insufflation using the formula (ΔV/ΔP). The relationship between demographic and anatomic variables and AC was investigated

Interventions

PROCEDURELaparoscopic surgery

effect of carbondioxide insufflation on abdominal compliance was evaluated

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 82 Years

Healthy volunteers

Inclusion criteria

Aged between 18 and 82 years ASA class I-III Elective abdominal surgery with laparoscopic technique \-

Exclusion criteria

Aged below 18 and above 82 ASA IV-V

Design outcomes

Primary

Measure	Time frame	Description
The factors affecting abdominal compliance	From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery	Effect of rectus muscle thickness and lateral abdominal muscle group thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

Secondary

Measure	Time frame
The factors affecting abdominal compliance	From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026