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Examination of Postdural Puncture Headache Frequency, Predisposing Factors and Treatment

Examination of Postdural Puncture Headache Frequency, Predisposing Factors and Treatment Applied in Patients Undergoing Spinal Anesthesia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06394024
Acronym
PDPH
Enrollment
400
Registered
2024-05-01
Start date
2023-11-01
Completion date
2024-03-31
Last updated
2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postdural Puncture Headache

Brief summary

Post-dural puncture headache (PDPH) is one of the most important complications of neuraxial blocks and lumbar interventions for cerebrospinal fluid (CSF) examination. It occurs due to tear in the dura mater and loss of cerebrospinal fluid (CSF) after intrathecal or epidural interventions.The incidence of PDPH depends on the thickness of the needle used and the type of tip. Headaches are more common with thick needles than with thin needles.In our study, postdural puncture headache in patients whose surgery was planned and spinal anesthesia was applied at Süleyman Demirel University faculty of medicine;frequency, predisposing factors, treatment intended to examine.

Detailed description

Different anesthesia techniques are applied to patients undergoing surgery. These are general anesthesia and regional (Spinal, Epidural, peripheral nerve blocks, etc.) anesthesia applications. Today, regional anesthesia is the most frequently preferred anesthesia method by anesthesiologists due to its low side effects. Spinal anesthesia is the temporary stopping of nerve conduction with a local anesthetic solution injected into the cerebrospinal fluid. It is one of the most commonly used regional anesthesia techniques today.Important advantages of regional anesthesia include the patient's continued spontaneous breathing, preservation of oropharyngeal reflexes, continuation of analgesia in the postoperative period, early mobilization, and short hospital stay.Post-dural puncture headache (PDPH) is one of the most important complications of neuraxial blocks and lumbar interventions for cerebrospinal fluid (CSF) examination. The incidence of PDPH is significantly higher in young people than in the elderly, in women compared to men, and in pregnant women compared to the normal population.In our study, spinal anesthesia cases will be examined. Patients with headache will be identified. Patients' demographic data (age, height, body weight, gender, comorbidities), ASA (American Society of Anesthesiologists) score, operation type, presence of headache etiology, needle type and diameter used, number of interventions and procedures. level, amount of local anesthetic given, adjuvant drugs added, experience of the practitioner, amount of fluid given, date and time of headache onset, treatment and procedure complications will be monitored and recorded in the form.

Interventions

None listed

Sponsors

Mustafa Soner Ozcan
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* \>18 years * ASA physical status class I, II and III * BMI \<40 kg/m² * Patients undergoing spinal anesthesia

Exclusion criteria

* ASA physical status class \> III * Severe cardiac, respiratory, hepatic, and renal disease * Refusing spinal anesthesia * History of local anesthetic allergy * Localized infection at the injection site * Coagulopathy * Anticoagulant drugs usage * History of chronic pain (migraine, sinusitis, etc.) * Alcohol and opioid addiction * Psychiatric diseases * Communication difficulties * Vertebral or chest wall abnormalities * BMI \> 40 kg/m²

Design outcomes

Primary

MeasureTime frameDescription
postdural puncture headache frequency6 months-rate of headache
is postdural puncture headache treatments successful?6 months-success of treatment participants were also asked about the success of their treatment; the answer was yes or no.
number of patient having postdural puncture headache6 months-number of participants
Number of patients receiving postdural puncture headache treatments6 months-number of participants
postdural puncture headache treatments6 months-rate of treatments,

Secondary

MeasureTime frameDescription
Number of patients obtained as a result of the relationship between postdural puncture headache and predisposing factors6 months-number of participants
Relationship between postdural puncture headache and predisposing factors6 months-rate of headache

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026