Treatment of Idiopathic Generalized Epilepsy
Conditions
Keywords
Levetiracetam, Valproate, Idiopathic generalized epilepsy
Brief summary
This study aimed to compare the long-term efficacy and safety of levetiracetam and valproate in treatment of idiopathic generalized epilepsy.
Interventions
DRUGLevetiracetam
Patients with idiopathic generalized epilepsy who were under treatment with levetiracetam
DRUGSodium valproate
Patients with idiopathic generalized epilepsy who were under treatment with valproate
Sponsors
Mazandaran University of Medical Sciences
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of juvenile myoclonic epilepsy or generalized tonic-clonic seizure alone * Regular monotherapy with levetiracetam or sodium valproate
Exclusion criteria
* Poor drug adherence * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Seizure free rate | 1 to 5 years | The percent of patients who remained seizure free on treatment |
| Time to first seizure | 1 to 5 years | The interval between start of treatment and recurrence of seizure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Retention rate | 1 to 5 years | The percent of patients who remained on treatment with levetiracetam or valproate |
| Time to withdrawal | 1 to 5 years | The interval between start and withdrawal of treatment |
Countries
Iran
Outcome results
None listed