Bronchiectasis Adult
Conditions
Keywords
bronchiectasis, Airway Clearance Technique
Brief summary
The goal of this prospective randomized controlled trial is to explore the efficacy and safety of Oscillation and Lung Expansion-a airway clearance technology-in bronchiectasis. Participants will receive Oscillation and Lung Expansion or postural drainage randomly in this study. and the symptom, quality of life scores and amount of expectoration will be compared between the two groups.
Interventions
A novel airway clearance technology
BEHAVIORALPostural drainage
A type of physical therapy used to treat respiratory diseases by changing the patient's body position so that sputum is drained down the respiratory tract so that it can be more easily expelled from the body.
Antibiotics were used in these patients.
DRUGMucolytic
Mucolytics were used in these patients.
Sponsors
Shanghai Pulmonary Hospital, Shanghai, China
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Patients will be randomized into one of the two groups. No cross-over of the study group will be made
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* patients with acute exacerbation of bronchiectasis
Exclusion criteria
* Haemoptysis greater than 50ml * state of endangerment * pneumothorax * Lung surgery history within 6 months * Severe heart, brain and nervous system diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sputum volume in 24h | 2 weeks |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bronchiectasis exacerbation and symptom tool | Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge | BEST score |
| Quality of life questionnaire-bronchiectasis | Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge | Qol-B score |
| Leicester Cough Questionnaire | Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge | LCQ score |
| Bronchiectasis Health Questionnaire | Assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 weeks post-discharge | BHQ score |
| Time to the first bronchiectasis exacerbation since randomization | Assessed at 4 weeks, 8 weeks and 12 weeks post-discharge | Time to the first bronchiectasis exacerbation since randomization |
Countries
China
Contacts
Primary ContactJin-Fu Xu, PhD
Outcome results
None listed