Labor Pain
Conditions
Keywords
Dexmedetomidine, Fentanyl, intrathecal, labor pain
Brief summary
As most woman experience agonizing pain throughout vaginal labor. Adjuvants were added to intrathecal bupivacaine aiming to improve the quality of analgesia. This study aimed to assess the efficacy and outcome of intrathecal dexmedetomidine and fentanyl in controlling pain during delivery.
Detailed description
Throughout vaginal deliveries, many women suffered from pain. providing suitable analgesia is crucial (Lupu et al., 2023). Spinal anesthesia can provide pain management (Parikh et al., 2018). Various types of analgesics can be combined to get the needed duration of perioperative analgesia. Dexmedetomidine has been used with effective pain management outcomes (Shrestha et al., 2023). Fentanyl can help pain relief in short duration procedures (Show et al., 2022).
Interventions
DRUGFentanyl
comparison between bupivacaine, bupivacaine and fentanyl.
DRUGDexmedetomidine
comparison between bupivacaine, bupivacaine and dexmedetomidine..
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* women planned for spontaneous vaginal delivery.
Exclusion criteria
* cardiac, liver or kidney disease, allergy to local anesthetics or the studied drugs, any contraindication of regional anesthesia and intrauterine growth retardation or fetal compromise.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| efficacy of intrathecal dexmedetomidine | 120 minutes | VAS |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| patient satisfaction | 2 hours | satisfaction score |
| mother's outocme | 1 and 5 minutes | APGAR |
Countries
Egypt
Outcome results
None listed