Obesity
Conditions
Brief summary
To establish an obesity specific disease cohort database and form a special disease cohort, so as to provide guarantee for carrying out high-quality real-world clinical research and clinical research.
Interventions
OTHERother
Observational studies do not involve intervention
Sponsors
RenJi Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients aged 18-75 years with simple obesity. Simple obesity diagnosis criteria: meet one of the following conditions 1. BMI≥25 kg/m2 2. Waist circumference for male/female ≥90/80 cm 3. Waist-to-hip ratio: 0.9 (male); 0.85 (female)
Exclusion criteria
* Patients aged 18-75 years with simple obesity. Simple obesity diagnosis criteria: meet one of the following conditions 1. BMI≥25 kg/m2 2. Waist circumference for male/female ≥90/80 cm 3. Waist-to-hip ratio: 0.9 (male); 0.85 (female)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MRI-PDFF intraperitoneal fat content, fasting and postprandial blood glucose, insulin, C-peptide, glycated hemoglobin, body weight, waist circumference, hip circumference | 5 years | For a specialized outpatient clinic for obesity, follow-ups should be conducted at 3 months, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years. During the trial period and the post-trial observation period, relevant safety indicators must be documented, analyzed statistically, and reported. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intestinal flora components, glucagon, gastrointestinal hormones GLP-1 and GIP, inflammatory immune indicators, etc | 5 years | For a specialized outpatient clinic for obesity, follow-ups should be conducted at 3 months, 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years. During the trial period and the post-trial observation period, relevant safety indicators must be documented, analyzed statistically, and reported. |
Countries
China
Contacts
Primary ContactJing Ma
Outcome results
None listed