Chronic Tonsillitis, Obstructive Sleep Apnea, Pregnancy
Conditions
Brief summary
This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) resulting from chronic tonsillitis on pregnancy outcomes. The hypothesis posits that chronic tonsillitis-induced OSA may exacerbate pregnancy complications and increase the risk of adverse pregnancy outcomes.
Interventions
OTHERexposure: OSA resulting from chronic tonsillitis
exposure: OSA resulting from chronic tonsillitis
Sponsors
Peking University First Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Pregnant women confirmed with chronic tonsillitis by clinical diagnosis and presenting symptoms. * Pregnant women with a confirmed diagnosis of OSA based on polysomnography or other validated sleep monitoring techniques. * Pregnant women who are willing to participate in the study and provide informed consent.
Exclusion criteria
* Pregnant women with other respiratory or sleep disorders that may confound the diagnosis of OSA. * Pregnant women with severe comorbidities or medical conditions that may significantly impact pregnancy outcomes. * Pregnant women who have undergone surgical treatment for chronic tonsillitis or OSA during the study period. * Pregnant women who refuse to participate in the study or are unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| preterm birth rate | 10 months |
Secondary
| Measure | Time frame |
|---|---|
| delivery methods | 10 months |
Other
| Measure | Time frame | Description |
|---|---|---|
| pregnancy complications | 10 months | — |
| neonatal birth weight | 10 months | birth weight of newborns measured in grams |
| neonatal length | 10 months | length of newborns measured in centimeters |
| Apgar score of newborns | 10 months | The Apgar score consists of five main indicators: skin color, heart rate, response to stimulation, muscle tone, and respiration. Each indicator is scored from 0 to 2, with a total score of 10. This scoring method serves as a guiding tool for the resuscitation of newborns with asphyxia and could provide a degree of predictive value for the neurological development of infants in the future. |
Contacts
Primary ContactXiaowan Du
Outcome results
None listed