Obstructive Sleep Apnea, Pregnancy
Conditions
Brief summary
This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) on pregnancy and fetal outcomes. The hypothesis posits that OSA may aggravate pregnancy complications, elevate the risk of adverse pregnancy outcomes, and potentially impact fetal development.
Interventions
DEVICEContinuous Positive Airway Pressure
The intervention in this study involves the use of Continuous Positive Airway Pressure (CPAP) treatment. CPAP is a commonly used therapy for obstructive sleep apnea (OSA) and other sleep-related breathing disorders. The principle of CPAP treatment lies in maintaining a constant airway pressure during sleep to prevent the collapse of the upper airway and ensure unobstructed breathing. The patient wears a mask connected to a CPAP machine, which generates a steady stream of air to provide the necessary pressure.
Sponsors
Peking University First Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Pregnant women with a confirmed diagnosis of OSA based on polysomnography or other validated sleep monitoring techniques. * Pregnant women who are willing to participate in the study and provide informed consent.
Exclusion criteria
* Pregnant women with other respiratory or sleep disorders that may confound the diagnosis of OSA. * Pregnant women with severe comorbidities or medical conditions that may significantly impact pregnancy outcomes. * Pregnant women who have undergone surgical treatment for chronic tonsillitis or OSA during the study period. * Pregnant women who refuse to participate in the study or are unable to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rate of pre-eclampsia/ eclampsia | 10 months |
Secondary
| Measure | Time frame |
|---|---|
| rate of preterm birth | 10 months |
Other
| Measure | Time frame | Description |
|---|---|---|
| birth weight | 10 months | birth weight of newborns measured in grams |
| length of newborns | 10 months | length of newborns measured in centimeters |
| The Apgar score of newborns | 10 months | The Apgar score consists of five main indicators: skin color, heart rate, response to stimulation, muscle tone, and respiration. Each indicator is scored from 0 to 2, with a total score of 10. This scoring method serves as a guiding tool for the resuscitation of newborns with asphyxia and could provide a degree of predictive value for the neurological development of infants in the future. |
Contacts
Primary ContactXiaowan Du
Outcome results
None listed