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Pilot Study - Monitoring the Nasal Microbiome and Viral Respiratory Infections in Newborn Hospitalized in Neonatalogy.

Pilot Study - Monitoring the Nasal Microbiome and Viral Respiratory Infections in Newborn Hospitalized in Neonatalogy. Metatranscriptomic Approach by New Generation Sequencing From High Respiratory Swabs.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06389383
Acronym
NEONATMICROBIO
Enrollment
38
Registered
2024-04-29
Start date
2022-12-21
Completion date
2024-11-13
Last updated
2025-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Newborn; Infection

Brief summary

The objective of our study is therefore to study the evolution of the respiratory microbiome of hospitalized newborns, its interaction with viral infections and their impacts on the evolution of newborns.

Interventions

OTHERNasal Swab

* Nasal swab once a week for the duration of the stay in intensive care unit/intensive care (procedure already carried out routinely to detect nasal staphylococcus once a week). * Nasal swab every 14 days when the newborn is hospitalized in routine care/kangaroo unit/hospitalization at home

Sponsors

University Hospital, Caen
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Newborn hospitalized in intensive care or neonatal intensive care. * Whose parents were able to be informed of the study and who signed consent. * Parents affiliate to the social security system

Exclusion criteria

* Refusal of parental consent * Parents who are minors or under guardianship, curatorship, safeguard of justice or legal protection. * Newborn having already left the hospital/returned home before inclusion * Hospitalization beyond the first 48 hours of life * Only palliative care.

Design outcomes

Primary

MeasureTime frame
rate of viral infectionsfrom baseline to end of hospitalization (up to 2 months)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026