Symphysis Onlay Bone Graft, Platelet Rich Fibrin, Xenograft, Horizontal Alveolar Ridge Augmentation, Esthetic Zone
Conditions
Brief summary
The aim of the study: was to evaluate whether mandibular symphysis Onlay autogenous bone graft mixed with Injectable PRF could offer any advantages for patients undergoing horizontal alveolar ridge widening regarding increase alveolar ridge width compared to mandibular symphysis Onlay autogenous bone graft mixed with Xenograft
Detailed description
Alveolar bone resorption is one of complications post-extraction complications where there is a reduction in the dimensions and quality of the alveolar bone. Alveolar bone resorption is known to occur over time, but resorption in the first few months of tooth extraction is known to be very significant. The ideal bone graft material should have osteoconductive, osteogenic, and osteoinductive properties and mechanical stability and be free from disease. Osteoconductive is a physical property of a material that provides a framework for the growth of blood vessels and osteoprogenitor cells in bone formation. Osteoinductiveness is the ability to stimulate stem cells to differentiate in mature cells through stimulation by local growth factors. Osteogenicity is the bone growth factors in bone grafts. Growth factors from PRF such as platelet-derived growth factor (PDGF), transforming growth factor (TGF), and insulin growth factor (IGF) are known to play a significant role in healing and bone regeneration to prevent excessive alveolar resorption after tooth extraction.
Interventions
Patients underwent mandibular symphysis Onlay bone graft mixed with injectable platelet rich fibrin (I-PRF) placement.
OTHERXenograft
Patients underwent mandibular symphysis Onlay bone graft mixed with Xenograft (InterOss® Anorganic Cancellous Granules).
Sponsors
October 6 University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Age from 20 to 40 years. * Both sexes. * Patients suffering from horizontal alveolar ridge deficiency in anterior maxilla with labio-palatal dimensions less than 4 mm. * Patients with adequate vertical ridge height compared to the neighboring alveolar bone. * Patients with good oral hygiene and adjacent teeth bounding the empty span (span ranged from 1 to 4 missing teeth), should have healthy periodontium, intact or properly restored. * Patients were apparently free from any systemic disease that may affect normal healing process of bone.
Exclusion criteria
* Patients suffering from any systemic diseases were excluded from the study. * Poor oral hygiene and motivation. * General contraindications to implant surgery. * Uncontrolled diabetes. * Irradiation, chemotherapy, or immunosuppressive therapy over the past 5 years. * Active periodontitis. * Psychiatric problems.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Alveolar ridge width | 6 months postoperative | Cone beam computed tomography (CBCT) was done to all patients to measure alveolar ridge width at the following intervals: pre-operative and 6 months postoperative. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bone density | 6 months postoperative | Cone beam computed tomography (CBCT) was done to all patients to measure bone density at the following intervals: pre-operative and 6 months postoperative. |
Countries
Egypt
Outcome results
None listed