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Cohort in Qianwan New District, Ningbo

Prevention and Control of Chronic Noncommunicable Diseases in Natural Population in Qianwan New District, Ningbo

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06387875
Enrollment
30000
Registered
2024-04-29
Start date
2023-11-01
Completion date
2027-06-30
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Non-Communicable Chronic Diseases, Stroke

Keywords

cohort, natural population, Non-communicable Chronic Disease

Brief summary

Our objective is to carry out research on prevention and control of noncommunicable chronic diseases, and establish a risk prediction mechanism for chronic diseases to promote early detection, early diagnosis and early treatment of chronic diseases in natural population in Qianwan District of Ningbo, significantly reduce medical costs and extend population life span.

Detailed description

1. Through baseline survey (cross-sectional survey) and prospective cohort design, the health status information and biological samples of residents in Hangzhou Bay Hospital were collected, and the physical, psychological and social adaptability information was collected through questionnaires and other forms, basic tests and omics measurements were carried out based on the collected samples to build a multi-dimensional data platform. 2. Develop a disease risk prediction model based on big data platform, conduct high-risk population screening and establish risk assessment files; In view of the common health problems in the study population, the key factors and effects of health status were analyzed comprehensively, and the corresponding mathematical model was established to form the prediction of health status. Finally to establish the stratified standard of population health status and provide effective health guidance. Questionnaire survey on epidemiology: The Hangzhou Bay Natural Population Cohort Questionnaire was designed according to the principles and requirements of cohort study. All respondents who entered the cohort will sign informed consent, receive face-to-face interview with uniformly trained investigators, and the questionnaire will be reviewed by quality control personnel for quality control. Physical examination: The examination contents include height, weight, blood pressure, waist circumference, hip circumference, hearing, vision, medical history and surgery, inbody composition, chest film, electrocardiogram, B-ultrasound, non-invasive arteriosclerosis examination, vascular endothelial ultrasound and other imaging examinations. Clinical biochemical test: 5-10 ml of blood, 20 ml of urine and 5 g of feces were collected (if necessary) according to the chronic non-communicable disease spectrum and clinical test requirements in Qianwan New District of Ningbo; The blood samples and urine were tested for biochemistry, liver and kidney function, blood lipids and electrolytes according to clinical testing requirements, as well as multi-omics indicators as needed. 3. Prospective study data: Follow-up of the cohort population (disease occurrence, death, migration, etc.) was conducted through annual active follow-up (telephone, interview, etc.) and passive follow-up, including data of all-cause death, incidence of any kind of diseases.

Interventions

None listed

Sponsors

Ningbo Hangzhou Bay Hospital
CollaboratorUNKNOWN
RenJi Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* 1\) Local permanent residents aged 18 and above (including residents with household registration, or residents without household registration but with a permanent job); * 2\) No serious physical disability, can communicate normally; * 3\) Participate voluntarily and sign informed consent.

Exclusion criteria

* 1\) Temporary resident and floating population; * 2\) There are serious health conditions unable to participate in the survey; * 3\) Those who are unwilling to accept the follow-up inspection of the project.

Design outcomes

Primary

MeasureTime frameDescription
death4 yearsMortality of all-cause disease were calculated by age, gender and area compared by different health management mode.
incidence of cardio-cerebrovascular diseases4 yearsIncidence of Cardiovascular and Cerebrovascular diseases were calculated by age, gender and area compared by different health management mode.
incidence of other non-communicable chronic diseases4 yearsIncidence of other non-communicable chronic diseases were calculated by age, gender and area compared by different health management mode.

Countries

China

Contacts

Primary ContactJun Pu, MD, PhD
pujun310@hotmail.com86-21-68383477
Backup ContactWei Zhang, PhD
zhangwei050080@renji.com86-13761780922

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026