Deep Endometriosis, Surgery
Conditions
Brief summary
TrEnd trial is aimed to collect data from consecutive patients undergoing segmental sigmoid colon/rectal resection for deep endometriosis. The main purpose of this project is to gather a large series of cases treated using standardized surgical procedures, allowing a precise evaluation of complications and long-term outcomes.
Interventions
PROCEDUREColorectal bowel resection
The TrEnd is a single-institutional retrospective/prospective study, conducted in a high-volume referral centre for the endometriosis diagnosis and management, with the aim of systematically collecting data from consecutive patients undergoing segmental sigmoid colon/rectal resection for deep endometriosis.
Sponsors
Casa di Cura Privata 'Malzoni - Villa dei Platani' S.P.A.
Study design
Observational model
CASE_ONLY
Time perspective
OTHER
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 55 Years
Inclusion criteria
* age \>/= 18 years; * presence of deep endometriotic nodule(s) infiltrating the tunica muscularis of the sigmoid colon/rectum.
Exclusion criteria
* age \<18 years: * presence of coexisting inflammatory bowel disease; * patients who have received previous pelvic radiotherapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To assess the rate of recurrence | 10 years | Rate/percentage |
| To document the surgical strategies adopted for treating patients with deep endometriosis undergoing to sigmoid colon/rectal resection | 10 years | Percentage |
| To assess the rate of complications | 10 years | Rate/percentage |
| To assess the rate of conversion to open surgery | 10 years | Rate/percentage |
| To assess the rate of endometriosis-free bowel resection margins | 10 years | Rate/percentage |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| To assess the intraoperative blood loss | 10 years | Median with IQR |
| To assess the operating time | 10 years | Median time with IQR |
| To assess the gastrointestinal function recovery | 10 years | Median days with IQR |
| To assess the duration of hospital stay | 10 years | Median days with IQR |
| To assess the reproductive outcomes | 10 years | Rate/percentage of pregnancies, normal full term deliveries, spontaneous and voluntary abortions |
Countries
Italy
Contacts
Primary ContactMario Malzoni, MD
Outcome results
None listed