Coronary Ectasia, Microbial Disease
Conditions
Keywords
microbiota, endothelium
Brief summary
Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ. In addition, the microbiota, through its metabolites, is involved in the pathophysiology or progression of a wide range of diseases, from atherosclerotic diseases to metabolic diseases and even neurological diseases. Among these metabolites, trimethylamine n-oxide metabolite has been shown to be particularly effective on atherosclerotic heart diseases.
Interventions
DIAGNOSTIC_TESTTaking blood for kit study
Taking blood for kit study (Elisa kit)
Sponsors
Necmettin Erbakan University
Konya Beyhekim Training and Research Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* over 18 years old * not having occlusive coronary artery disease * having coronary ectasia
Exclusion criteria
* patients with chronic kidney disease, * revascularized coronary artery disease, * previously documented critical coronary stenosis, * acute or chronic inflammatory disease, * rheumatologic disease, * known active malignant disease, * heart failure, * moderate-to-severe valvular pathology * patients who were on any steroid or immunosuppressive therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| death | 1 month | Death from any cause within the last month |
Countries
Turkey (Türkiye)
Outcome results
None listed