Abdominal Cancer, Abdomen Disease
Conditions
Keywords
major abdominal surgery, M-TAPA, opioid consumption, postoperative analgesia
Brief summary
This study aims to examine the effects of M-TAPA applied for postoperative analgesia in patients who had major intraabdominal surgery on the postoperative pain score, the change in the postoperative total opioid requirement and the side effects.
Detailed description
The investigators seperated the patients into two groups as M-TAPA applied group and control group.In group M-TAPA, M-TAPA block was performed bilaterally with 20 mL of 0.2% bupivacaine under ultrasound guidance at the end of surgery. No block was performed in the control group. The participants were administered morphine through patient controlled analgesia (PCA) pump with a bolus dose of 1 mg, 15 min lockout interval. The postoperative pain scores (the numeric rating scores (NRS)), total opiod consumption in the first 48 h, and opioid related side effects were recorded.
Interventions
OTHERM-Tapa Block
M-TAPA block was performed bilaterally with 20 mL of 0.2% bupivacaine under ultrasound guidance at the end of surgery
Sponsors
Marmara University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
Yes
Inclusion criteria
* patient \> 17 years old * ASA score 1-3 * undergoing major intra-abdominal surgery
Exclusion criteria
* ASA IV patients * patients with known neurological or psychiatric disorders * patients with clinically significant cardiovascular, respiratory, hepatic, renal or metabolic disease * patients with long-term drug (opioid) or alcohol dependence * patients with BMI\>30 * patients with intellectual disability * patients who developed massive bleeding and coagulopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Opioid Consumption | Postoperative 24 hours | The postoperative opioid consumption |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| NRS Scores | postoperative 24 hours | Numeric Rating Scale score (rating from 1 to 10. 1:no pain to 10: worst pain ever) |
| the need for rescue analgesia | postoperative 24 hours | if NRS\>4: apply rescue analgesia: the total count of rescue analgesia need |
| side effects | postoperative 24 hours | nausea- vomiting |
Countries
Turkey (Türkiye)
Outcome results
None listed