Periodontitis
Conditions
Brief summary
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid
Detailed description
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis. 60 patients: 30 with periodontitis and 30 healthy controls. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise). Measurements are taken before and after initial periodontal treatment in the periodontal subjects.
Interventions
Probin Pocket Depth reduction in millimetres before and after treatment
Sponsors
University of Catania
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Masking description
Sealed envelopes
Intervention model description
Non-surgical periodontal treatment Subgingival biofilm ultrasonic debridement with MINST or Q-SI
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of Periodontitis
Exclusion criteria
* Periodontal treatment * Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probing Pocket Depth | 6-months | Reduction in Probing Pocket Depth after treatnebt |
Countries
Italy
Contacts
Primary ContactGaetano Isola
Backup ContactRosalia Leonardi
Outcome results
None listed