The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia

Four-quadrant Transversus Abdominis Plane Block Versus Intrathecal Morphine in Gynecological Cancer Surgeries: a Single-center Retrospective Study.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06382376

Enrollment

Registered

2024-04-24

Start date

2023-06-01

Completion date

2024-03-01

Last updated

2024-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological Cancer Surgery, Regional Anesthesia Morbidity

Keywords

gynecological cancer surgery, periferal block, neuraxial block

Brief summary

The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries. The key question(s) it aims to answer are: \[Is intrathecal morphine more effective in postoperative analgesia?\] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores and postoperative opioid use.

Detailed description

Our study was designed retrospectively. The investigators evaluated analgesia methods in patients who underwent laparoscopic or open surgery due to gynecological cancer between June 2023 and December 2023. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block on postoperative analgesia and opioid use. Group 1: Intrathecal morphine administered group Group 2: Four quadrant transversus abdominis plane block applied group

Interventions

PROCEDUREIntrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group

Intrathecal morphine administered group and Four quadrant transversus abdominis plane block applied group

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* 18 years * Patients who have undergone gynecological cancer surgery

Exclusion criteria

* \<18 years * Those with missing data

Design outcomes

Primary

Measure	Time frame	Description
postoperative numerical rating scale	24 hours postoperatively	Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable.

Secondary

Measure	Time frame	Description
postoperative opioid use	24 hours postoperatively	Our secondary aim was to evaluate opioid demand and consumption amounts in the postoperative 24 hours.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026