Rectal Cancer
Conditions
Brief summary
The investigators propose to use flexible endoscopy combined with transanal total mesorectal resection to further reduce anal injury.
Detailed description
Endoscopic technique has become an indispensable part of Natural orifice transluminal endoscopic surgery (NOTES). However, the upper gastrointestinal tract is easy to cause severe leakage complications, which mainly limits the application of endoscopy in rectum. Herein, investigators propose purse suture closing distal rectum and full-layer incision of the rectal wall using flexible endoscopic from anal to assist in hybrid transanal total mesorectal resection (taTME).Further reduce the damage of anus caused by taTME.
Interventions
PROCEDUREFlexible colonoscope assisted hybrid transanal total mesorectal resection
Endoscopic pursestring suture (EPSS) was performed at the distance from 1cm to the inferior edge of the tumor by a double-channel flexible colonoscope. An endoloop was inserted through one channel. Meanwhile, the endoclips was inserted through the other channel one by one to fix the endoloop around the rectal wall. And then the endoloop was tightened slowly. After completing the routine lavage lumen, a full-thickness, circumferential dissection was performed by flexible colonoscope following taTME surgical principle until it converged with the laparoscopy group.
Sponsors
Sun Yat-sen University
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. Age between 18 and 80 years old 2. Confirmed rectal adenocarcinoma cancer pathologically 3. tumor location ≦ 12 cm from the anal margin 4. Willing and able to provide written informed consent for participation in this study
Exclusion criteria
1. distant metastasis before surgery 2. more than one colorectal tumor at diagnosis 3. familial adenomatous polyposis 4. recurrent rectal cancer 5. undergo transanal minimally invasive surgery 6. undergo palliative treatment 7. undergo emergency surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Success rate of operation | 1 years after the surgery | Whether it is necessary to switch to other surgical methods |
Countries
China
Contacts
Primary ContactLiang Kang, MD. and Phd.
Outcome results
None listed