Long COVID, Myocardial Injury
Conditions
Keywords
2D-STE, resonance breathing, Myocardial Injury, Long Covid-19
Brief summary
An investigation of the efficacy of resonance breathing training in the rehabilitation of patients with Long covid-related myocardial injury
Interventions
OTHERResonance breathing
Resonant breathing was used on the subjects, using nasal inhalation and oral exhalation, for a total of 12 weeks.
Sponsors
Chengdu Sport University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
1. Age between 18 and 60 years; 2. According to the WHO definition: one or more systemic involvement present 3 months after the diagnosis of a new crown infection, and at least 2 of these months cannot be explained by other diseases 3. 2D-STE suggestive of GLSAVG: -17% ≤ men ≤ -10%, -18% ≤ women ≤ -10%; 4. Consent for enrollment based on the degree of myocardial injury, as diagnosed by a clinician; 5. Signing the informed consent form with the consent of the patient or his/her family members
Exclusion criteria
* (1) Previous history of coronary atherosclerotic heart disease and heart failure; (2) Combination of severe arrhythmia or cardiogenic shock; (3) Combination of severe hypertension, hypertrophic cardiomyopathy, valvular disease of moderate or higher grade, acute myocarditis or pericarditis; (4) Combination of any disease that severely affects limb movement, such as musculoskeletal system disease or severe hepatic or renal insufficiency; (5) Combination of progressive malignant tumors, infectious diseases, bleeding disorders, autoimmune diseases, etc; Those who have serious mental illness and are unable to cooperate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| New YorkHeart Association (NYHA) | 12weeks | The scale is divided into four levels Grade 1 is unrestricted activity. Daily physical activity does not cause significant shortness of breath, fatigue or palpitations Grade 2 is a mild limitation of activity. Asymptomatic at rest, daily activities may cause significant shortness of breath, fatigue or palpitations Grade 3 is marked limitation of activity. May be asymptomatic at rest, but may cause significant shortness of breath, fatigue, or palpitations with less than daily activity. Grade 4 is symptomatic at rest, with discomfort associated with any physical activity. Class IVa for those who can move around indoors or at the bedside without intravenous drug administration; Class IVb for those who cannot get out of bed and require intravenous drug administration. |
| left ventricle global longitudinal strain, LVGLS | 12weeks | The magnitude of overall longitudinal myocardial strain in the left ventricle on two-dimensional speckle tracking echocardiograms as an average of the peak longitudinal strain in all myocardial segments. The normal range is (-25% to -17%) in men and (-25% to -18%) in women. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| hypertension | 12weeks | Blood pressure included both systolic and diastolic blood pressure and was observed before and after the intervention for any reduction in blood pressure. |
| Average heart rate | 12weeks | One-minute average heart rate (at rest). |
Contacts
Primary ContactRui Li
Backup ContactRui Li
Outcome results
None listed