Skin Cancer
Conditions
Brief summary
In this clinical study, photoacoustic imaging will be used on patients with suspected skin cancer (primarily melanoma, basal cell carcinoma, and squamous cell carcinoma) to determine the tumor borders both superficially and at a depth.
Detailed description
The study will employ multispectral photoacoustic imaging in the spectral range between 680-970 nm to scan suspected skin tumors both in vivo and ex vivo. The hyperspectral data will then undergo rigorous spectral analysis with the objective to identify the spectral fingerprints associated with healthy tissue and tumor. Thereafter, a classification algorithm will be used to determine whether a pixel in the acquired image more likely identifies with healthy tissue or tumor, which is then repeated for all pixels in the images. As such, a 3D image can be reconstructed in which the tumor is visibly contrasted from healthy tissue. Achieving this goal will facilitate the diagnostic procedures and greatly reduce waiting times, clinical costs and potential patient suffering.
Interventions
None listed
Sponsors
Region Skane
Lund University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients scheduled to perform surgical excision of lesion(s) suspected to be tumors.
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tumor thickness | Enrollment is anticipated to last 1 year + final analyse 6 months | Compare the estimated tumor thickness of tumor lesion with the provided thickness from the histopathological investigation. |
| Tumor size | Enrollment is anticipated to last 1 year + final analyse 6 months | Compare the estimated tumor surface size of tumor lesion with the provided thickness from the histopathological investigation. |
Countries
Sweden
Outcome results
None listed