End Stage Renal Failure, Secondary Hyperparathyroidism
Conditions
Brief summary
The purpose of this study is to characterize the quality of life change in patients undergoing parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure.
Detailed description
Study participants will be asked questions about age, gender, education level, clinical symptoms, intensities of depression and anxiety, etc, and they will also be questioned regarding the prior quality of life score, as measured by the health-related quality of life 36-item Short-Form (SF-36) survey before surgery. Then, study participants will be contacted at one, three, six months, and 1 year after surgery, and asked questions about their SF-36 score, depression, and anxiety intensity.
Interventions
Study the progression of quality of life.
Sponsors
Chunling Jiang
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age: ≥18 years old; * Patients scheduled for parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure
Exclusion criteria
• Patients refuse to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Measure quality of life scores change with respect to time | up to 1 year | Quality of life will be assessed by the 36-Item short form health survey scale, Subjects complete one response from a range of options for each of the 36 questions. A combination of item response is then aggregated to calculate a score for each of the eight dimensions listed. The scores for each dimension range from 0 to 100, with higher scores indicating better health status |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Measure anxiety and depression score change with respect to time | up to 1 year | The anxiety and depression were evaluated using Hospital anxiety and depression Scale (HADS). The HADS consists of 14 questions, with 7 items each for the anxiety and depression subscales. The score for each item ranges from 0 to 3 points, and scores are summed to yield a separate score for anxiety (HADS-A) and depression (HADS-D). |
| Measure bone pain scores change with respect to time | up to 1 year | The bone pain is evaluated using numerical rating scale (NRS). NRS scores range from 0 to 10 points, with 0 points representing no pain, 1-3 points representing mild pain, 4-6 points representing moderate pain, 7-9 points representing severe pain and 10 points representing the strongest pain. |
| Length of hospital stay | through study completion, an average of 1 week | Determined by the number of days from admittance to discharge |
Contacts
Primary ContactChunling Jiang, PhD
Backup ContactChunling Jiang
Outcome results
None listed