Insulin Resistance, Abdominal Obesity, Diabetes
Conditions
Brief summary
Obesity and diabetes share a common insulin resistance pathway and contribute to chronic hyperglycemia. Both high-intensity interval exercise (HIIE) and focused ultrasound (FUS) have been explored in the context of managing insulin resistance in diabetic individuals with abdominal obesity, though they operate through different mechanisms and have different implications.
Detailed description
Forty diabetic females aged 25 to 35 years old and body mass index was ≥ 30 kg/m², will participate in this study. They will be assigned into two equal groups, Group A will receive high intensity interval exercise 2 times per week for 4 months in addition to intermitted fasting diet. Group B will receive focused ultrasound 2 times per week for 4 months in addition to intermitted fasting diet. Assessment of abdominal obesity will be applied pre and post treatment through measuring Body mass index (BMI), Waist circumference (WC) in addition to Value of HbA1c and HOMA-IR hormone will be measured to determine effect of treatment on insulin resistance.
Interventions
HIIT is a type of interval training exercise. It incorporates several rounds that alternate between several minutes of high intensity movements followed by short periods of lower intensity movements 2 times per week for 4 months.
OTHERFocused ultrasound
Focused ultrasound will be applied over the anterior abdominal, two sessions per week for 4 months, each session 40 minutes.
Sponsors
Badr University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
They will be recruited from El\_shinnawy physical therapy Centre. * All are suffering from abdominal obesity * Their age between 25-35 years old * Their body mass index more than 30 kg/m2, * Their waist circumference ranged from 88 cm * The fat thickness at the treatment area was at least 2.5 cm
Exclusion criteria
* Females having any skin diseases in the abdomen. * Female suffering from any physical or mental disorders. * Females suffering from abdominal scars or hernia * Females didn´t take any medication that might affect their weight all over the study period. * Females complaining from any cardiovascular disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body mass index | Before starting the study and after 4 months of treatment | The weight and height of each woman in both groups will be measured to calculate the body mass index (BMI) |
| Waist circumference | Before starting the study and after 4 months of treatment | Assessment of waist circumference of each woman by the tape measurement |
| Skin fold | Before starting the study and after 4 months of treatment | The thickness of the abdominal fold will be measured using skinfold calipers to provide information on changes in subcutaneous fat in the abdominal region. |
| Value of HbA1c and HOMA-IR hormone | Before starting the study and after 4 months of treatment | Value of HbA1c and HOMA-IR hormone will be measured to determine effect of treatment on insulin resistance. |
Contacts
Primary ContactZeezy Soliman Eraky, Lecturer
Backup ContactNoha Ahmed Fouad Abd El Rahman, Lecturer
Outcome results
None listed