Elevated Blood Pressure, Perimenopause
Conditions
Keywords
Physical activity, Women's health, Minority health, Behavior change, Hypertension prevention
Brief summary
This study will test the effects of a physical activity intervention among midlife Hispanic women.
Detailed description
The menopausal transition in midlife is a critical juncture where women experience life transitions and adverse physiological and psychological changes that increase the risk for hypertension and cardiovascular diseases in later life. Physical activity improves blood pressure, biomarkers of hypertension, sleep, mood, and well-being; however, Hispanic women meet physical activity recommendations at lower levels than non-Hispanic White women. The investigator will examine the feasibility of the physical activity intervention among sedentary midlife Hispanic women in the menopausal transition with elevated blood pressure, exploring changes in physical activity and health.
Interventions
BEHAVIORALPhysical activity intervention
Physical activity
Sponsors
The University of Texas Medical Branch, Galveston
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
45 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
1. Female 2. Hispanic by self-report 3. Able to speak and read English 4. Sedentary 5. Age 45-50 6. Diagnosed with elevated blood pressure or objectively measured systolic blood pressure 120-139 mmHg and/or diastolic blood pressure 80-89 mmHg averaged from ≥ 2 measures on ≥ 2 outpatient visits 7. Symptoms consistent with the menopause transition (persistent difference of ≥7 days in the length of consecutive cycles; persistence is defined as recurrence within 10 cycles of the first variable length cycle) 8. Apparently healthy 9. Self-reported ability to engage in moderate intensity physical activity 10. Access to a smart device that is compatible with a Fitbit application
Exclusion criteria
1. Self-reported physical activity of ≥150 minutes per week 2. Answered yes to any question on the Physical Activity Readiness (PAR-Q+) questionnaire 3. Post-menopausal (12-months without a menstrual cycle) 4. Diagnosed hypertension 5. Cardiovascular, respiratory, neurological, renal, endocrine, gastrointestinal and/or psychiatric diseases, or any cancers 6. Previous hysterectomy, oophorectomy, and/or uterine ablation 7. Medication to treat hypertension, elevated glucose, cholesterol, depression, anxiety, and insomnia 8. Hormonal medication via any route or implants 9. Tamoxifen 10. Pregnant, planning to become pregnant, or breastfeeding 11. Planning to move out of the Galveston/Houston area in the next 18 months 12. Current participation in another physical activity study or program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Days the activity monitor was worn | Baseline to 6-months | Objectively measured days the wearable activity monitor was worn during the intervention period |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physical activity as measured by minutes of moderate-vigorous intensity physical activity at 6 months | Baseline to 6-months | Mean daily minutes of moderate-vigorous intensity physical activity taken from accelerometers for a 7 day period |
| Physical activity as measured by minutes of moderate intensity physical activity at 6 months | Baseline to 6-months | Mean daily minutes of moderate intensity physical activity taken from accelerometers for a 7 day period |
| Physical activity as measured by minutes of vigorous intensity physical activity at 6 months | Baseline to 6-months | Mean daily minutes of vigorous intensity physical activity taken from accelerometers for a 7 day period |
| Physical activity as measured by minutes of light intensity physical activity at 6 months | Baseline to 6-months | Mean daily minutes of light intensity physical activity taken from accelerometers for a 7 day period |
| Systolic blood pressure | Baseline to 6-months | Change in systolic blood pressure (mmHg) |
| Diastolic blood pressure | Baseline to 6-months | Change in diastolic blood pressure (mmHg) |
| Physical activity as measured by minutes of total physical activity at 6 months | Baseline to 6-months | Mean daily minutes of total physical activity taken from accelerometers for a 7 day period |
Other
| Measure | Time frame | Description |
|---|---|---|
| Abdominal circumference | Baseline to 6-months | Change in abdominal circumference (cm) |
| Body mass index | Baseline to 6-months | Change in body mass index (kg/m2) |
Countries
United States
Contacts
Primary ContactLisa Thibodeaux, BSN, RNC-OB
Outcome results
None listed