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Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor.

Functional Recovery in the First Six Postoperative Months of Cancer Patients Undergoing Lower Limb Resection and Reconstruction. An Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06376539
Acronym
FISIO-ONCO
Enrollment
100
Registered
2024-04-19
Start date
2024-04-10
Completion date
2026-01-31
Last updated
2026-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Neoplasm, Rehabilitation

Keywords

bone tumor, physiotherapy, functional recovery

Brief summary

The aim of the present study is to describe the course of functional recovery of patients with musculoskeletal tumours and undergone resection and reconstruction operations of lower limbs in the first six months post-surgery, differentiating them on the basis of the anatomical level involved.

Detailed description

Retrospective observational study will be conducted. The evaluation of the patients clinical recovery progress will take place at three different times: during the hospital stay postoperative, at 3 and 6 months after surgery. Different outcome measures will be considered in order to provide a complete picture of the patients functional recovery and their change.

Interventions

None listed

Sponsors

Istituto Ortopedico Rizzoli
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
12 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* All participants undergone lower limb resection and reconstruction with localisation of the disease to the pelvis, femur femur, tibia and foot bones. * All participants undergone soft tissue resection surgery on the of the lower limb * All types of oncological diagnoses will be taken considered: osteosarcoma, Ewing and others.

Exclusion criteria

* Participants who undergo at our Institute only the surgical treatment while continuing adjuvant treatment at other centres * Participants for whom no rehabilitation treatment has been activated during adjuvant treatment at our Institute

Design outcomes

Primary

MeasureTime frameDescription
Toronto Extremity Salvage Score (TESS)at 3 months after surgeryPerson's level of independence. It is measured through 30 questions relating to 30 activities of daily living to be answered by the patient. The total score is reported from 0 to 100. A higher score indicates a greater degree of autonomy. A higher score indicates a greater degree of autonomy.

Secondary

MeasureTime frameDescription
Range of motion (ROM)at 3 months after surgeryThe range of motion of the main joints of the lower limbs (hip, knee or foot), measured with a goniometer
Rang of motion - 2 (ROM)at 6 months after surgeryThe range of motion of the main joints of the lower limbs (hip, knee or foot), measured with a goniometer
Number of participants able to walkup to 1 weekNumber of participant that are able to walk and aids used for walking
Time Up and Go -2 (TUG)at 3 months after surgeryTime it takes a person to get up from a chair, walk three metres, turn around, return to the chair and sit down again is measured.
Time Up and Go (TUG)at 6 months after surgeryTime it takes a person to get up from a chair, walk three metres, turn around, return to the chair and sit down again is measured.
Muscle Strengthat 3 months after surgeryGrades of Muscle Strength from 0 (no contraction) to 5 (best strength)
Number of day from surgery to first walkingup to 1 weekThe number of day that participants needs to recover ambulation after surgery
Muscle Strength-2at 6 months after surgeryGrades of Muscle Strength from 0 (no contraction) to 5 (best strength)

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026