Colonic Neoplasms
Conditions
Keywords
endoscopy submucosal dissection, colonic neoplasms, colonic surgery
Brief summary
Propose a one-piece endoscopic resection such as endoscopic submucosal dissection (ESD) rather than surgery for benign lesions and superficial T1 cancers colorectal cancers offers comparable efficacy with better tolerability. This approach is all the more in the rectum, even for giant lesions lesions (over 8cm), as rectal surgery is particularly morbid, with particularly morbid, with a functional impact that can impact, whereas rectal ESD is less prone to complications fewer complications than in the colon. Colonic ESD for giant lesions is a longer and more morbid more time-consuming and morbid than for smaller lesions, the question of colonic surgery in this indication. this indication. In order to compare the morbidity data of patients of giant lesions with those of colectomy, a control group colectomy, a surgical control group will be set up, including patients including patients having undergone surgery for in situ T1 or T2 in situ colon cancer. Surgical resections of resection of benign lesions is generally not indicated not indicated and would not provide the necessary necessary for a comparison. T3 and T4 lesions with their own their own morbidity will be excluded.
Interventions
None listed
Sponsors
University Hospital, Brest
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Group A : * Patients from the FECCO cohort * who have undergone ESDresection of a giant lesion, defined by a fresh specimen measuring more than 8cm long axis, of the colon * Between September 2019 and 2022 * Major * Patient affiliated to a social security scheme Group B: * Patients from the Registre des Tumeurs Digestives Registry (Brest University Hospital) * Having undergone colectomy with lymph node dissection for intramucosal colonic adenocarcinoma, T1 or T2 colonic adenocarcinoma * Between September 2019 and 2022 * Adults * patient affiliated to a social security scheme
Exclusion criteria
* \- rectal lesion ; * patients under legal protection (guardianship, curatorship, ...) or deprived of liberty ; * refusal to participate.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 30 days severe morbidity | 30 days | Comparison of severe morbidity (Clavien dindo ≥ IIIb) at 30 days of patients who underwent DSM for giant colonic lesion (group A) to that of patients who underwent surgery surgery equivalent to that which would be performed for such a lesion (group B) |
Secondary
| Measure | Time frame |
|---|---|
| morbidity of ESD group | 30 days |
| comparison of morbidity in both groups | 30 days |
| reintervention | 30 days |
| stomia | 30 days |
| length of hospital stay | 30 days |
| readmission | 30 days |
| mortality | 30 days |
| risk factors for morbidity | 30 days |
Countries
France
Outcome results
None listed