Oxygen Deficiency
Conditions
Keywords
creatine, guanidinoacetic acid, oxygen saturation, brain
Brief summary
The main aim of this randomized controlled trial is to evaluate cerebral blood oxygenation after 7-day administration of a creatine-guanidinoacetic acid (GAA) mixture in healthy adults before, during, and after a series of cognitive tests.
Interventions
DIETARY_SUPPLEMENTSupplement
Dietary supplement containing creatine and guanidinoacetic acid
DIETARY_SUPPLEMENTPlacebo
Inert substance
Sponsors
University of Novi Sad, Faculty of Sport and Physical Education
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-30 years * Absence of metabolic disorders or other health complications * Provision of signed informed consent
Exclusion criteria
* History of dietary supplement use within the preceding 4 weeks * Lack of consent to randomization * Concurrent participation in other studies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Brain oxygen saturation | Change from baseline brain oxygen saturation at 2 weeks | Percentage of oxygen saturation in prefrontal brain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hemoglobin index | Change from baseline hemoglobin index at 2 weeks | Concentration of hemoglobin index in prefrontal brain |
Countries
Serbia
Outcome results
None listed