Colorectal Cancer, Colorectal Neoplasms
Conditions
Keywords
colorectal cancer, colorectal cancer surgery, colorectal neoplasym, transversus abdominis plane, transversus abdominis plane block
Brief summary
Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. Thus, TAP block is widely implemented in perioperative management of colorectal cancer patients. Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries.
Detailed description
Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. With the increasing use of ultrasound guidance during peripheral nerve blocks, trunk blocks such as the transversus abdominis plane (TAP) block are widely used for analgesia after abdominal surgery. The advantages of TAP block include being less invasive than epidural analgesia, lower incidence of hypotension, and shorter hospital stay. Due to these advantages, TAP block has become a widely preferred method. Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries. The study will be conducted in a tertiary oncology hospital in Turkey and 84 colorectal cancer patients will be included.
Interventions
DRUGBupivacain
Ultrasonography (USG) guided bilateralTAP block:20 ml %0,25 concentration bupivacain
DRUGbupivacain+dexmedetomidine
Ultrasonography (USG) guided bilateral TAP block: 20 ml %0,25 concentration bupivacain+ 0.5 mcg/kg dexmedetomidine
Sponsors
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* colorectal cancer diagnosis * undergoing colorectal cancer surgery
Exclusion criteria
* allergic reaction to local anesthetics * bleeding anomalies * infection in TAP block area
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Analgesic effectiveness of bupivacain and bupivacain+dexmedetomidine combination in colorectal cancer surgery | postoperative day two | Numeric Rating Scales of two groups in postoperative period. The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable" |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORBeyza Seker, MD
Resident MD
Outcome results
None listed