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Effect of Platelet Rich Plasma on Outcome of Narrow Band UVB in Treatment of Vitiligo; Clinical and Histopathological Study

Effect of Platelet Rich Plasma on Outcome of Narrow Band UVB in Treatment of Vitiligo; Clinical and Histopathological Study

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06370650
Enrollment
30
Registered
2024-04-17
Start date
2023-12-08
Completion date
2024-06-30
Last updated
2024-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Management of Stable Vitiligo

Brief summary

For each patient, one side of body will be treated with NB-UVB alone while the other side will be treated with NB-UVB therapy in addition to intradermal injection of PRP every 2 weeks. Patients will be photographed at the first visit, in the middle and at the end of therapy. Each patient will sign a written consent form to be included in the study and to be photographed.

Interventions

PROCEDUREplatelet rich plasma, narrow band UVB

Role of PRP in treating stable vitiligo

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
15 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

Patients with stable non segmental vitiligo. (Absence of koebnerization, absence of new lesion and absence of widening of the existing lesions). Patients have more than 15 years. \-

Exclusion criteria

Patients have active vitiligo (appearance of new lesion, history of koebnerization). Pregnant and lactating women. History of keloid formation. Anemia (hemoglobin level \<10gm/dl), thrombocytopenia (platelet count \<100,000 /µL), coagulopathies or patients on anticoagulant therapy and patients with iron deficiency. Patients taking drugs that prolong bleeding time such as Aspirin and vitamin E Patients taking treatment of vitiligo in last 2 months

Design outcomes

Primary

MeasureTime frameDescription
Improvement of vitiligowithin 6 monthsincrease repigmentation score

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026