Psoriatic Arthritis
Conditions
Brief summary
Psoriasis is one of the most common immunemediated chronic inflammatory skin disorders.
Detailed description
Psoriasis is one of the most common immunemediated chronic inflammatory skin disorders. Beside genetic factors, several environmental factors such as injuries, infections, stress, drugs, and immune defect take part in autoimmune pathogenesis of the disease. In addition, it has been reported that some hormones may also have a role in the pathogenesis of psoriasis, due to their effects on keratinocytes proliferation. Studies revealed that sex hormones manifest a variety of biological and immunological effects in the skin which modulate the natural course of psoriasis. Approximately 20-30% of patients with psoriasis may also have psoriatic arthritis, which often causes significant musculoskeletal pain that significantly impairs quality of life (QoL). Although sexual dysfunction is a common complaint, affecting 30 to 70% of psoriasis patients, few studies have analyzed the impact of psoriasis and psoriatic arthritis on quality of sexual life.
Interventions
BEHAVIORALThe effect of psoriatic Arthritis
to assess the frequency rates of sexual problems and associated factors in a cohort of married females with Psoriatic arthritis, and to investigate the correlation between sex hormones profile ( estrogen and progesterone level) and female sexual function in Psoriatic arthritis patients.
Sponsors
Egymedicalpedia
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* The study will focuses on the relationship between the FSD and PsA; * The healthy controls will derive from a population within the same geographic area and ethnic background as PsA; * Used the same questionnaires/instruments of FSFI to diagnose FSD
Exclusion criteria
* pregnancy, * breastfeeding * being sexually inactive * having a partner with sexual dysfunction, * refusing to participate, or * being unable to read * Females with any sexual transmitted disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of female sexual function | 6 months | To identify and understand the mechanisms of sexual problems in Psoriatic arthritis Patients in Qena university hospital. |
Countries
Egypt
Contacts
Primary ContactEisa Hegazy, Professor
Outcome results
None listed