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Neurophysiological and Neuropsychological Evalution in Healthcare Workers

Neurophysiological and Neuropsychological Evalution in Healthcare Workers of Stress Condition

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06368999
Acronym
EEGCOV
Enrollment
40
Registered
2024-04-16
Start date
2020-05-27
Completion date
2021-01-09
Last updated
2024-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress Disorders, Post-Traumatic

Brief summary

The goal of this observational study is to compare in participant population the effect of stress condition on cerebral EEG activity Participants will do an 8 minutes EEG registration. Researchers will compare EEG activity of heathcare workers.

Interventions

DIAGNOSTIC_TESTEEG

registration of 8 minutes of EEG

Sponsors

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE

Intervention model description

study of brain EEG activity

Eligibility

Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* healthcare workers

Exclusion criteria

* neurological disorders

Design outcomes

Primary

MeasureTime frameDescription
EEG activityimmediately after the outbreak of the pandemic (first session) and almost 6 months later (second session).The subjects were instrumented with 19 bridge silver and silver chloride electrodes fitted on a plastic prewired head cap and placed on the scalp according to the 10-20 system (namely: Fp1, Fp2, F3, F4, F7, F8, Fz, C3, C4, Cz, P3, P4, Pz, T3, T4, T5, T6, O1, and O2), with an electroconductive paste applied between the electrodes and the skin to guarantee optimal connection The signals were recorded with a 512 Hz sampling frequency and filtered by an offline first order zero-phase Butterworth band-pass filter, with cutoff frequencies set, respectively, at 1.6 and 70 Hz to remove frequencies outside the range of interest. After this pre-processing, the main EEG rhythms and dominant frequencies were extracted by spectral and connectivity analyses. Delta (1.6-4 Hz), theta (4-8 Hz), alpha (8-13 Hz), beta (13-30 Hz), gamma1 (30-50 Hz), and gamma2 (50-70 Hz) frequency bands were considered.

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026