Postoperative Sore Throat
Conditions
Keywords
ketamine gargling, Post-operative sore throat, endotracheal tube complications
Brief summary
Tracheal intubation often causes trauma to the airway mucosa, leading to postoperative sore throat (POST), which has been reported to occur in 21-65% of cases. While considered a minor complication, POST can contribute to postoperative discomfort and patient dissatisfaction.
Detailed description
Patients have ranked POST as the eighth most adverse effect during the postoperative period. Various methods, both non-pharmacological and pharmacological, have been explored to mitigate POST with varying degrees of success. Non-pharmacological approaches include using smaller-sized endotracheal tubes, lubricating the tube with water-soluble jelly, employing careful airway instrumentation, ensuring intubation after full relaxation, employing gentle oropharyngeal suctioning, minimizing intracuff pressure, and deflating the tracheal tube cuff completely before extubation, all of which have been reported to reduce the incidence of POST.
Interventions
DRUGGargle with ketamine
The patients asked to gargling with ketamine solution in the preoperative waiting area after explain the whole procedure and the goals of the study.
Sponsors
Al-Azhar University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Adult patients from both sex and aged between 18 and 45 years. * All participants were scheduled for elective laparoscopic appendectomy or cholecystectomy under general anesthesia. * Classified as ASA (American Society of Anesthesiologists) I or II. * Intubation duration is less than 90 minutes.
Exclusion criteria
* Patients classified as ASA III or higher. * Patients exhibiting symptoms of sore throat prior to entering the operating room, or presenting with any respiratory illness or signs of respiratory infection. * Patients who smoke. * Patients with a history of allergy to drugs used in this study. * Patients who are addicted to steroid drugs (inhaled or oral). * Patients with predicted difficult airway and intubation, indicated by a Mallampati score of II or higher. * Obese patients with a BMI exceeding 35. * Patients with neurological diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sore throat | 2, 6, 12, and 24 hrs. postoperatively | A sore throat is characterized by pain, scratchiness, or irritation in the throat, typically aggravated by swallowing. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cough | 2, 6, 12, and 24 hrs. postoperatively | Coughing and bucking while intubated on emergence from general anesthesia unfortunately occurs in approximately 40% of patients |
| Hoarseness of voice | 2, 6, 12, and 24 hrs. postoperatively | Hoarseness of voice is a common complication after tracheal intubation and may be very limiting for a patient after anesthesia. |
Countries
Iraq
Contacts
Primary ContactMinistry O Health
Backup ContactHussein A Al-Jaberi, PhD
Outcome results
None listed