Kidney Stone
Conditions
Brief summary
Nearly 10% of the Belgian population suffer from kidney stone disease. Recent reviews reported that kidney stones represent an underestimated risk factor for further kidney function deterioration. Preventive measures are recommended in lithiases patients to prevent the formation of new stones. The individual effects of different medicated prosthetic interventions have been documented in clinical trials. However, there is little data on the effectiveness of combining these different preventive measures in routine clinical practice (real-world context). Patients with kidney stone disease require a complete metabolic assessment. The three main factors contributing to the stone's formation are the patient's metabolism, diet and lifestyle. Metabolic work-up is recommended by the American Urology Association to identify and correct the factors responsible for urinary stone formation such as hypercalciuria, hyperoxaluria, hyperuricuria, hypocitraturia or abnormalities of urinary pH. The metabolic work-up includes at minimum the 24h urine test, a blood test and spot urine test. Dietary habits and lifestyle are assessed by means of a questionnaire. The CHU Brugmann Hospital has a specialized multidisciplinary clinic for renal lithiases and mineral metabolism. Preventive personalized and interdisciplinary care in CHU Brugmann consists of a full metabolic work-up allowing the identification of lithogenic risk factors by nephrologists, dietary assessment by specialized dieticians and specific treatment protocol associated with regular follow-up. The aim of this study is to evaluate, in the context of a retrospective single-center cohort study, the effect of preventive personalized and interdisciplinary care on the evolution of all urinary lithogenic risk factors and the recurrence of kidney stones (rate of renal colics, emergency room admissions, and urological interventions).
Interventions
None listed
Sponsors
Agnieszka Pozdzik
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients of the CHU Brugmann Hospital who fulfill the criteria of active or past history of kidney stone, from 01/01/2018 till 31/10/2023 * Minimum follow-up time of 2 months with biochemical and clinical results available
Exclusion criteria
\- None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of acute renal colics | From first patient consultation till 31/10/2023 | Number of acute renal colics |
| Number of emergency admissions | From first patient consultation till 31/10/2023 | Number of emergency admissions |
| Number of surgeries | From first patient consultation till 31/10/2023 | Number of surgeries |
| Number of hospitalizations | From first patient consultation till 31/10/2023 | Number of hospitalizations |
| Identified genetics abnormalities | From first patient consultation till 31/10/2023 | List of identified genetics abnormalities |
| Wisconsin questionnaire | From first patient consultation till 31/10/2023 | Changes in the quality of life in the patients (evolution of the scoring of the Wisconsin questionnaire) |
| Kidney function outcome | Status at 31/10/2023 | Kidney function outcome |
Countries
Belgium
Contacts
Primary ContactSirika Chhem
Backup ContactAgnieszka POZDZIK
Outcome results
None listed