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Time of Exercise Re-training With Chronic Obstructive Pulmonary Disease (COPD)

Effect of Time of Exercise Re-training on Functional Capacity in Individuals With Chronic Obstructive Pulmonary Disease (COPD)

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06366113
Acronym
CHRONOBIO
Enrollment
90
Registered
2024-04-15
Start date
2024-01-02
Completion date
2026-07-01
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Diseases

Keywords

respiratory diseases, pulmonary rehabilitation, chronic obstructive pulmonary disease, biological clock

Brief summary

Pulmonary rehabilitation (PR) is an effective intervention for reducing hospital readmissions, secondary events, and mortality in patients with respiratory pathologies. The program should not be improved by introducing new subjects such as circadian rhythm.

Detailed description

Respiratory diseases are a leading cause of death in developed countries. To avoid complications and recurrences, secondary prevention in patients with respiratory diseases is essential. Pulmonary rehabilitation (PR) is a well-established and effective treatment that is supervised by medical professionals and conducted in dedicated centres. It has been shown to reduce hospital readmissions, secondary events, and patient mortality. The timing of reconditioning is crucial. Previous studies have indicated that training times affect strength and power gains. Additionally, the time of day for training can significantly impact progress in aerobic capacity. Disturbances to the biological clock can have consequences for people with respiratory pathologies, particularly an alteration in muscular function. Therefore, studying the temporal specificity of exercise re-training in patients with respiratory diseases is of interest.

Interventions

OTHERPulmonary rehabilitation

Pulmonary rehabilitation includes : * Exercise re-training with resumption of physical activities * therapeutic patient education

Sponsors

Michaël RACODON
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* Age ≥ 18 years * Patient with chronic obstructive pulmonary disease (COPD) * Registered for respiratory re-education and rehabilitation at the Clinique de la Mitterie * Number of rehabilitation sessions at least 18 over 4 weeks * Written informed consent signed by the patient * Membership of a social security

Exclusion criteria

* \- cardiovascular contraindications to exercise * unstable respiratory status (uncompensated respiratory acidosis) * conditions interfering with the pulmonary rehabilitation process (progressive neuromuscular disease, psychiatric illness)

Design outcomes

Primary

MeasureTime frameDescription
6-minute walk test (6MWT)15 minutesWalking distance in a test

Secondary

MeasureTime frameDescription
Sit to stand test (STT)1 minuteThe number of sit-to-stand repetitions during the test.
Single arm curl Test (SAC)1 minuteThe number of bends during the test
Time limit test (Time-lim)0 to 900 secondesEndurance exercise holding time in seconds
Hospital Anxiety and Depression Scale (HAD)10 minutes. The maximum mark for each score is 21 and the minimum mark is 0. The higher the score, the more depressed or anxious the person.Hospital Anxiety and Depression score
Pittsburgh Sleep Quality Index10 minutes. The total score ranges from 0 to 21, with 0 indicating no difficulties and 21 indicating major difficulties.Sleep quality score
Single-leg stance test (SLT)1 minuteThe time for balance

Countries

France

Contacts

Primary ContactMichaël RACODON, PhD
mracodon@clinique-mitterie.com+33320223457

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026