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Rescue Extracranial Vertebral Stenting in Tandem Occlusions

Rescue Extracranial Vertebral Stenting in Tandem Occlusions

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06365294
Acronym
REVET
Enrollment
9
Registered
2024-04-15
Start date
2020-12-31
Completion date
2024-06-08
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Stroke, Ischemic Stroke, Acute, Vertebro Basilar Ischemia

Keywords

tandem occlusions, posterior circulation, rescue extracrnial stenting

Brief summary

The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion. The investigators reported whether the additional rescue extracranial stenting improved clinical outcome by modified Rankin Scale (mRS) score within 3 months after the procedure

Detailed description

Acute vertebrobasilar artery occlusion is one of the cerebrovascular diseases with high disability and mortality rates. Although mechanical thrombectomy has recently been demonstrated an effective treatment for large vessel occlusions of posterior circulation, the treatment strategies depending on the specific pathophysiology. Tandem occlusion in posterior circulation is less frequently than in anterior one, comprises severe stenosis or occlusion of the extracranial vertebral artery ipsilateral to its intracranial and basilar occlusion. The recent studies showed the benefit of the distal-to-proximal approach, there were many tecniques to achieved the successful recanalization. Besides, the use of Dotter technique allowed 8F guiding catheter to cross the extracranial lesions easily and save the procedural time. However, the Diagnosis 5F-Dotter, like the Dilator-Dotter, has not been mentioned in previous studies. Therefore, the aim of the our study was to assess the improvement of outcomes at 3 months posttreatment in patients receiving rescue extracranial vertebral stenting

Interventions

PROCEDURERescue extracranial stenting

Rescue extracranial stenting in tandem occlusions

Sponsors

Dr. Cuong Tran Chi
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* Age \> 18 years old * Onset to treatment time \< 24 hours * NIHSS \> 5 * pc-ASPECTS ≥ 5

Exclusion criteria

* Premorbid mRS \> 2 * Extensive, bilateral brain-stem infarction on neuroimaging * Cerebellar mass effect on neuroimaging * Loss to follow-up

Design outcomes

Primary

MeasureTime frameDescription
The good 3-month outcome rate3 monthsThe good 3-month outcome rate was accessed by modified Rankin Score (mRS ≤ 2).

Countries

Vietnam

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026