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Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms

Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06365138
Enrollment
500
Registered
2024-04-15
Start date
2024-01-01
Completion date
2030-12-01
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Aneurysm

Keywords

Aortic Rupture, Physical stress, Emotional Stress, Rupture Risc, Follow-Up, Activity

Brief summary

It is currently unclear what activities aneurysms are involved in at the time of rupture. The aim of the study is to determine the activity performed at the time of aneurysm rupture.

Detailed description

The scientifically proven risk factors that significantly favor the rupture of an aortic aneurysm are female gender, the maximum diameter of the aortic aneurysm and the patient's current smoking status. However, no analysis of the occupation performed at the time of aortic rupture of an abdominal aortic aneurysm has yet been carried out. High arterial systolic blood pressure can promote aortic rupture. Blood pressure peaks can occur during physical exertion, for example when lifting heavy loads or during defecation. Patients with an existing intact aortic aneurysm are currently advised to avoid such behaviors as a preventive measure. This includes, among other things, the practice of strength training or certain types of sport. This can subsequently lead to a reduction in quality of life, although this cannot currently be substantiated by scientific data. There is also no current guideline recommendation in this regard. Furthermore, the role of stress and / or emotionally stressful events in connection with the occurrence of aortic ruptures has not yet been recorded in the literature. There is work on this in connection with aortic dissections, which postulates that an increase in emotional or psychological stress can lead to acute hypertension, which can cause a previously damaged aorta to rupture. A similar pathomechanism would also be conceivable for the rupture of aortic aneurysms. There are indications that, in addition to gender-specific differences in the occurrence of aortic ruptures, there is also a different risk of rupture based on certain pre-existing conditions, dietary habits and age.

Interventions

BEHAVIORALBahaviour at the time of an aortic aneurysm rupture

Questionnaire and patient interview, diary for day of rupture and the three previous days

Sponsors

Epidemiology, Medical Faculty, University Augsburg
CollaboratorUNKNOWN
University Hospital Augsburg
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* inclusion of all patients with ruptured aortic aneurysm in Augsburg University Hospital * Written consent to participate in the study by the patient or their legal representative

Exclusion criteria

* Lack of consent

Design outcomes

Primary

MeasureTime frameDescription
Occupation at the time of the aortic aneurysm ruptureOccupation at the day of the aortic rupture and the three days priorOccupation at the time of the aortic aneurysm rupture

Countries

Germany

Contacts

Primary ContactTobias Warm, MD
tobias.warm@uk-augsburg.de+49821400161068
Backup ContactYvonne Gosslau, MD
yvonne.gosslau@uk-augsburg.de+49821400161977

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026