Dry Eye Syndromes
Conditions
Keywords
Dry Eye diagnosis, Tear ferning
Brief summary
Application of tear ferning test for clinical dry eye diagnosis
Detailed description
Comparing dry eye patients' tear ferning structure with non-dry eye patients' to develop a protocol for easy and costless diagnosis in ophthalmology.
Interventions
OTHERwith/without dry eye syndrome
compare tear ferning structure between dry eye and non-dry eye patients
Sponsors
Chung Shan Medical University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Aged between 20 and 65 years * For dry eye disease group: * Schirmer's test results between 5 - 10 mm * Tear Film Break Up Time less than 10 seconds * Ocular Surface Disease Index of more than 25
Exclusion criteria
* Those have diabetes, hypertension or other chronic diseases * No evident ocular diseases such as cornea disease, cataracts, vitreous degeneration, glaucoma, and retinopathy. * Belong to vulnerable groups(pregnancy woman, prisoner, ethical minorities, economic or educationally disadvantaged subjects, disabled individuals such as those at terminal stage of tumorigenesis, blindness, terminal ill individuals)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Schirmer's test | 5 minutes | to assess tear secretion volume |
| Tear film breakup time | 20 seconds | to assess tear quality |
| Ocular surface health evaluate | 3 minutes | To assess the health status with Lissamine green stain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Ocular surface disease index | 20 minutes | A questionnaire to assess the health status on ocular surface A final score is calculated which ranges from 0 to 100 with scores 0 to 12 representing normal, 13 to 22 representing mild dry eye disease, 23 to 32 representing moderate dry eye disease, and greater than 33 representing severe dry eye disease. |
| Intraocular pressure | 2 minutes | to determine the effects of intervention on intraocular pressure |
Countries
Taiwan
Outcome results
None listed