Cardiovascular Prevention
Conditions
Brief summary
Cardiovascular diseases represent one of the main public health problems being the leading cause of morbidity, disability and mortality. In recent decades, the global prevalence and cardiovascular disease mortality has increased, with 23.6 million annual deaths expected by 2030. In Europe, mortality per year is equal to 2.2 million women and 1.9 million men, representing 47% and 37% of all deaths respectively. In Italy, the situation in terms of deaths due to cardiovascular diseases it is in line with the world ranking and European, being responsible for 44% of all deaths. The only interventional or pharmacological approach is neither effective nor sustainable. The most deaths from cardiovascular diseases are due to atherothrombotic events, which are attributable to a series of risk factors, most of which are modifiable. Turns out itself as a targeted action on these factors with the aim of safeguarding the state of health cardiovascular, may represent the best applicable strategy. It is therefore necessary structure and activate prevention programs aimed at the general population and groups of subjects at higher risk.
Interventions
Assessments of physical activity level and functional capabilities (aerobic capacity, muscular strength and power, flexibility
The 6 Minute Walk Test is a sub-maximal exercise test used to assess aerobic capacity and endurance. The distance covered over a time of 6 minutes is used as the outcome by which to compare changes in performance capacity.
OTHERSF-36, Euro-Qol 5D-5L, Perceived stress scale-10, Pittsburgh Sleep Quality Index, Depression Anxiety Stress scale- 21.
Evaluation of the quality of life, the psychological sphere (anxiety, stress, depression) and the quality of sleep
OTHERMEDAS
Evaluation of adherence to the Mediterranean diet
OTHERIntima-media thickness (IMT)
Bmode ultrasonography
BIOLOGICALBlood sampling
Measurement of parameters for defining cardiovascular risk and biomarkers.
BIOLOGICALStool Sample Culture Test
Evaluation of Gut Microbiota
Sponsors
Maria Cecilia Hospital
Study design
Allocation
NA
Intervention model
SEQUENTIAL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
No
Inclusion criteria
* primary prevention: age ≥ 30 years with a negative history of cardiovascular events * secondary prevention: age ≥ 30 years with a negative history of cardiovascular events
Exclusion criteria
* severe obesity * high-grade renal failure * severe and/or dialysis * oncological disease in active phase * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measure of body mass index | 12 months | BMI Assessment |
| Adherence to the Mediterranean diet | 12 months | Mediterranean Diet Adherence |
| blood test to check cholesterol levels | 12 months | Assessment of hypercholesterolemia |
| blood pressure measurement | 12 months | Evaluation of Diastolic Blood Pressure |
| blood glucose test | 12 months | evaluation of blood glucose |
Countries
Italy
Contacts
Primary ContactElena Tenti
Outcome results
None listed