Lung Cancer, Lung Embolism, Pneumonia, Radiation Exposure
Conditions
Brief summary
Evaluation of ultra low dose protocols and Iomeron 400 contrast in PCD-CT
Interventions
RADIATIONComputed Tomography
Computed Tomography CHEST
Sponsors
University of Zurich
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* CT SCAN for pulmonary nodule detection/follow up * CT SCAN for pneumonia detection/follow up
Exclusion criteria
* under 18 * BMI over 30
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dose Reduction by new scanner | through study completion, an average of 1 year | mSv per exam will be recorded. This value will be put in correlation to weight (Kg), height (cm) and BMI. |
| stable Image Quality in reduced dose scans | through study completion, an average of 1 year | Recorded values compared in 2 populations-different contrast agents by using qualitative&quantitative methods Qualitative:diagnostic certainty, assessability of lung structure/lesions,diagnostic reliability, Quantitative:Assessment of tissue composition,diagnostic performance measurements Attenuation/sealing measurement (HU), signal-to-noise ratio (SNR), contrast-to-noise ratio ,size dimensions of lung structure/lesion in three dimensions in millimeters Tissue composition assessment diagnostic performance measurements (sensitivity, specificity, accuracy) diagnostic confidence: 1-4 Theses measurements will be put in correlation to the scan dose (mSv) per patient, forming two groups with matched BMI (kg/m\^2) |
Countries
Switzerland
Outcome results
None listed