Colorectal Cancer
Conditions
Keywords
rectal cancer, anterior resection, LARS
Brief summary
Sphincter sparing surgery is oftentimes associated with bowel dysfunction complaints, namely the low anterior resection syndrome (LARS). The LARS questionnaire is widely used to assess this syndrome. With advances in colorectal surgery, sparing sphincter surgeries are gaining popularity. But symptoms after surgery can affect the quality of life which has psychomotor effects. Low anterior resection syndrome score is a worldwide known questionnaire. Many countries have accredited validation and translation of this questionnaire, but to our knowledge; it is the first time in Egypt.
Interventions
OTHERLARS score questionnaire
LARS score questionnaire is filled by the patient after anterior resection for rectal cancer to study the quality of life
Sponsors
Zagazig University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Age more than 18 * Diagnosed patients with rectal adenocarcinoma and who received low anterior resection with anastomosis creation or after a minimum 6 months interval after stoma reversal. * Tumors of the rectum (2-15 cm) from anal verge
Exclusion criteria
* • cognitive dysfunction * Having a history of inflammatory bowel disease or any disease with bowel function impairment namely, Crohn's disease, irritable bowel syndrome, ulcerative colitis or others. * Age less than 18 * Metastatic cancer or tumor recurrence * Rectal tumors within 2 cm from anal verge( abdominoperineal)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| age | from 2017 to 2022 | age of the patients in years was recorded from patient records |
| sex | from 2017 to 2022 | sex of patients was recorded from patient records |
| medical disease | from 2017 to 2022 | medical disease like diabetes and hypertension was recorded from patient records |
| site of tumor | from 2017 to 2022 | tumor site was determined in Cm from anal verge by colonoscopy |
| neoadjuvant therapy | from 2017 to 2022 | history of neoadjuvant therapy before surgery was obtained from patients records |
| site of anastmosis | from 2017 to 2022 | site of anastmosis after resection was recorded as colo-rectal or colo-anal |
| type of meso-rectal excision | from 2017 to 2022 | excision of meso-rectum was recorded if it was partial or complete |
| adjuvant therapy | from 2017 to 2022 | it was recorded from patients records if he\\she had chemo- or radiotherapy post-operatively |
| type of surgery | from 2017 to 2022 | from records; surgery was open or laparoscopic |
| type of anastmosis | from 2017 to 2022 | type of anastmosis(hand sewen or stappled) obtained from records |
| LARS score | from 2017 to 2022 | obtained by LARS questionnaire filled by the patient during follow up, it was formed of five questions with different scores on answer choices, interpretaion (0-20) means no LARS, (21- 29) means minor LARS, (30-42) means major LARS |
Countries
Egypt
Outcome results
None listed