Primary Dysmenorrhea
Conditions
Keywords
Dysmenorrhoea, Serum progesterone level, Visual analogue scale, Menstrual symptoms questionnaire
Brief summary
This study will be conducted to determine the correlation between the levels of serum progesterone and Menstrual Symptoms In Young Females with primary dysmenorrhea.
Detailed description
One hundred adult females with primary dysmenorrhea will participate in this study. They will be recruited from the Gynaecological outpatient clinic, Kasr El Ainy University Hospital, Cairo, Egypt Many studies reported that primary dysmenorrhea was the result of increased prostaglandin, especially prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) which produced the effect through the cyclooxygenase pathway, and further led to uterine ischemia hypoxia. Nevertheless the relationship between the serum progesterone level and menstrual symptoms was not completely clear. Hence, this study will investigate the association between the serum progesterone level and menstrual symptoms in young females with primaryf dysmenorrhea.
Interventions
None listed
Sponsors
Cairo University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
17 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
1. One hundreds adult females were suffered from primary dysmenorrhea. 2. Their age was ranged from 17 to 24 years. 3. Their body mass index was ranged from 20 to 25 kg/m2.
Exclusion criteria
* Any participant will be excluded from the study if they have: 1. Irregulars or infrequent menstrual cycles. 2. Pacemaker, Myasthenia gravis, hyperthyroidism, active tuberculosis and psychosis. 3. Pelvic pathology.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum progesterone level | 1 month | Blood samples will be taken by physician for each girl, and will send to laboratory center to measure the progesterone level in the blood. The normal serum progesterone level at 21st day is 4-20 ng |
| Pain intensity | 1 month | It will be measured by Visual analogue scale. It is 10 cm line with values ranging from 0 to 10. 0 indicates no pain nd 10 indicates the worst pain. |
| Physical and psychological menstrual symptoms | 1 month | It will be measured by menstrual symptoms questionnaire. It is 25 items split into two categories which used to assess the physical and psychological symptoms associated with dysmenorrhea. The score on each item ranged from 1 (never) to 5 (always) with a higher composite score indicating more symptoms |
| Correlation between serum progesterone level and pain | 1 month | The correlation between serum progesterone level and pain intensity measured by the VAS will be conducted |
| Correlation between serum progesterone level and menstrual symptoms | 1 month | The correlation between serum progesterone level and menstrual symptoms measured by the menstrual symptom questionnaire will be conducted |
Countries
Egypt
Outcome results
None listed