Skip to content

Artificial Intelligence-supported Reading Versus Standard Double Reading for the Interpretation of Magnetic Resonance Imaging in the Detection of Local Recurrence for Nasopharyngeal Carcinoma: a Randomised Controlled Multicenter Study

Artificial Intelligence-supported Reading Versus Standard Double Reading for the Interpretation of Magnetic Resonance Imaging in the Detection of Local Recurrence for Nasopharyngeal Carcinoma: a Randomised Controlled Multicenter Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06356441
Enrollment
10400
Registered
2024-04-10
Start date
2024-04-30
Completion date
2026-04-30
Last updated
2024-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Intelligence Supported Image Reviewing

Keywords

artificial intelligence, image reviewing, magnetic resonance imaging

Brief summary

The aim of this randomized controlled study is to investigate whether the previously developed artificial intelligence model can triage post-radiotherapy magnetic resonance images of patients with nasopharyngeal carcinoma and assist radiologists in their interpretation.

Interventions

DIAGNOSTIC_TESTAI

An artificial intelligence model predicts the risk and contours of local recurrence for MR images and triages them before radiologists interpret them.

Sponsors

Sun Yat-sen University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with treatment naive nasopharyngeal carcinoma who had finished radiotherapy for 6 months or more * The previous magnetic resonance imaging examination had showed complete remission in the primary site * Images are acquired using a 3T magnetic resonance imaging device, including unenhanced T1-weighted and T2-weighted sequences and contrast-enhanced T1-weighted sequences

Exclusion criteria

* Patients are enrolled in this study for a specific magnetic resonance imaging scan and not for subsequent follow-up magnetic resonance imaging scans.

Design outcomes

Primary

MeasureTime frame
sensitivitythrough study completion, an average of 2 years

Secondary

MeasureTime frame
the sensitivity in the subgroups of different rT-stagethrough study completion, an average of 2 years
specificitythrough study completion, an average of 2 years
positive predictive valuethrough study completion, an average of 2 years
the incidence of cases whose recurrent risks and contours cannot be provided by the AI modelthrough study completion, an average of 2 years
total time of interpretation for all the MR imagesthrough study completion, an average of 2 years
the rate of discussion with a third radiologistthrough study completion, an average of 2 years
the detection rate of local recurrence in the AI-supported reading groupthrough study completion, an average of 2 years
negative predictive valuethrough study completion, an average of 2 years

Countries

China

Contacts

Primary ContactFang-Yun Xie
xiefy@sysucc.org.cn+8602087342926
Backup ContactPu-Yun OuYang
ouyangpy@sysucc.org.cn+8602087342926

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026