A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1

Light Exposure Tracker in Alzheimer's Disease.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06356337

Enrollment

Registered

2024-04-10

Start date

2024-02-22

Completion date

2024-08-15

Last updated

2025-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's Disease, Mild Cognitive Impairment

Brief summary

The purpose of this research study is to investigate the relationship between reminder messages sent via text and compliance with a daily morning light intervention designed to advance the circadian clock. Twenty healthy adults will be recruited to participate in a randomized, cross-over study where daily messages are, or are not, provided to remind participants to carry out the intervention.

Interventions

DEVICELight goggles

Green light goggles worn for 1 hour each morning for two weeks

BEHAVIORALDaily reminder test message

Participants will receive daily text message reminding them to use light goggles each morning

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

55 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* healthy adults over the age of 55 * score of 25 or greater on MoCA

Exclusion criteria

* Severe sleep apnea * restless leg syndrome * obstructing cataracts * macular degeneration * diabetic retinopathy * glaucoma * use of sleep medications * brain disease

Design outcomes

Primary

Measure	Time frame	Description
Saliva samples for melatonin levels	Baseline and 2-weeks post-intervention for each Arm	Serial saliva samples will be collected to calculate dim light melatonin onset.

Secondary

Measure	Time frame	Description
Sleep time using actigraphy	worn all 12 study weeks	Sleep time will be calculated from the actigraph. The wrist actigraph measures activity during the day and how well you sleep at night. The actigraph software will calculate the amount of time spent in bed sleeping.
Light exposure using the Speck	worn all 12 study weeks	The Speck light meter will be used to collect overall light exposure.The Speck light meter uses a photosensor to measure the amount of light study participants are exposed to each day.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026