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Prehab for Lung and Esophageal Cancer

Prehab for Lung and Esophageal Cancer: Optimizing Well-being for Better Outcomes

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06354959
Enrollment
25
Registered
2024-04-09
Start date
2024-06-01
Completion date
2027-01-01
Last updated
2024-08-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise, Neoplasm of Lung, Neoplasms, Surgery

Brief summary

Research indicates that individuals diagnosed with lung or esophageal cancer who enter treatment with higher functional capacities, improved body composition, and better nutrition status tend to experience better outcomes and a higher quality of life. The primary objective of a prehabilitation health coaching program is to enhance the overall health and well-being of patients before they undergo major surgery.This personalized 8-week program encompasses elements such as nutrition, smoking cessation, sleep hygiene, and movement, equipping participants with the knowledge and tools needed to adopt healthier lifestyles.

Detailed description

The purpose of this study is to explore the implementation, feasibility and effectiveness of a community-based prehabilitation health coaching program, including nutrition, smoking cessation, sleep hygiene and movement for individuals scheduled to undergo surgery for lung or esophageal cancer.. Participants will have the option to engage in a one-on-one prehabilitation health coaching program tailored to their needs, led by a Qualified Exercise Professional (QEP). The personalized prehabilitation plan will encompass 4-6 in-person or virtual meetings before surgery, including a structured movement plan, education on smoking cessation, sleep quality, stress reduction, mindfulness, and nutrition. Post-surgery, the QEP will provide support through counselling and scheduled sessions for a month after surgery and include one session while the patient is in hospital. This research adopts a repeated measure, mixed-methods approach. Participants will undergo three clinical assessments at different stages: baseline, pre-surgery, and 4-6 weeks post-surgery. The findings from this study will guide future grant applications aimed at funding larger studies and the implementation of prehabilitation as part of standard of care in lung and esophageal cancer patients in Nova Scotia. Central to the research endeavor is the driving question: How can a community-based prehabilitation program be successfully implemented in the community, and can it lead to improved functional outcomes in patients undergoing surgery for lung or esophageal cancer? This overarching question provides the study with its core focus and serves as a guiding force throughout the research process.

Interventions

BEHAVIORALPrehabilitation

8-week community based prehab program

Sponsors

Dalhousie University
CollaboratorOTHER
Nova Scotia Health Authority
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Diagnosed with lung or esophageal cancer * Scheduled to receive surgical intervention in minimum 2-weeks * Surgeon approval * Able to read and write in English * \>18 years of age

Exclusion criteria

* Not able to provide informed consent

Design outcomes

Primary

MeasureTime frameDescription
Feasibility - Participant Experience2 yearsExit interview is used to assess factors influencing participant selection of intervention type/setting, adherence to and satisfaction with the health coaching program
Feasibility- Attendance2 yearsAttendance is calculated as the percentage of exercise sessions completed by the total number of available exercise sessions over the 8-10-week intervention.
Feasibility- Recruitment2 yearsParticipant accrual as defined as the number of eligible participants who consent to participate
Feasibility- Participant fidelity2 yearsParticipant adherence to prescribed exercise intervention
Feasibility - Safety2 yearsAdverse and serious adverse events
Feasibility - Retention/Attrition2 yearsPercentage of participants who complete the 12-week intervention

Secondary

MeasureTime frameDescription
Resting Heart rate8-10 week changeResting heart rate
Grip strength8-10 week changeTo test overall body strength
Resting blood pressure8-10 week changeresting systolic and diastolic blood pressure
Functional Assessment of Cancer Therapy - Lung OR Esophageal (FACT-L/ FACT- E)8-10 week change44 item that measures multidimensional quality of life
Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F)8-10 week changea 13-item questionnaire that evaluates an individual's self-reported fatigue during their usual daily activities over the past week
5x chair stand8-10 week changeTo test functional strengths, risk of falling and overall leg strength and endurance
Stair climb test8-10 week changeTo test functional strength, balance and agility

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026