Skip to content

Propensity to Hospitalize Patients From the ED in European Centers.

Propensity to Hospitalize Patients From the ED in European Centers.An Observational Retrospective Quality-of-care Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06354764
Acronym
eCREAM-UC1
Enrollment
162000
Registered
2024-04-09
Start date
2025-09-22
Completion date
2027-02-01
Last updated
2026-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergency Medicine

Brief summary

The peer-to-peer comparison means center-to-center comparison, which requires adjusting for possible differences among centers to be fair and convincing. The first step to reach this goal is to develop a predictive model that accurately estimates each patient's probability of being admitted, starting from clinical conditions and boundary variables. Such a model would make it possible to calculate, for each ED, the expected hospitalization rate; that is, the hospitalization rate that would have been observed if the ED had behaved like the average of the EDs that provided the data to build the model itself. Comparing the observed hospitalization rate in the single ED with the expected rate derived from the model provides a rigorous method of comparing the department with the average performance, taking into account the characteristics of the patients treated and the conditions under which the ED operated. In other words, the predictive model represents the benchmark against which each ED is evaluated.

Interventions

OTHERno intervention

no intervention

Sponsors

Mario Negri Institute for Pharmacological Research
Lead SponsorOTHER
Astir s.r.l.
CollaboratorINDUSTRY
Centre Hospitalier Universitaire Vaudois
CollaboratorOTHER
Orobix Life S.r.l.
CollaboratorUNKNOWN
Fondazione Bruno Kessler
CollaboratorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Adult * Arrived at emergency department between 1 January 2021 and 31 December 2023

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frameDescription
Create two separate databasesSeptember 2024 - September 2025To create two separate databases (one for each of the two subgroups considered) on all patients who presenteding to the participating EDs over a defined period, containing the information considered important to study both the propensity to hospitalize these patients and their 30-day mortality
Multivariable modelsSeptember 2025 - September 2026To develop two multivariable models that predict the probability that patients presenting to the ED with dyspnea (first model) or after a TLoC (second model) will be admitted to the hospital
Adjusted comparisonSeptember 2025 - September 2026To provide the participating EDs with an adjusted comparison of the hospitalization rates for the patients with selected symptoms, to improve the quality of care.

Countries

Italy

Contacts

CONTACTChiara Pandolfini
chiara.pandolfini@marionegri.it0039 02 39014 253
CONTACTGiulia Ghilardi
giulia_irene.ghilardi@marionegri.it0039 035 4535 389
PRINCIPAL_INVESTIGATORGuido Bertolini, MD

Istituto Di Ricerche Farmacologiche Mario Negri

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 21, 2026