Describe Relations Between qCON and qNOX Indicies During Propofol-Remifentanil General Anesthesia

Describe Relationship Between qCON and qNOX of the CONOX Monitor During General Anesthesia Perfromed With Propofol and Remifentanil Target Controlled Infusion (TCI)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06349681

Enrollment

Registered

2024-04-05

Start date

2024-04-01

Completion date

2024-10-01

Last updated

2024-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia Brain Monitoring

Keywords

Anesthesia brain Monitoring, TIVA-TCI, CONOX

Brief summary

Detailed description

CONOX is a neuromonitoring EEG- device for sedation (qCON) and analgesia (qNOX) monitoring during general anesthesia. It is unknown on how the indicies can differentiate themselves so aim of this study is to determine the relationship bwtween the 2 indicies, as well as with EMG, Concentration of Propofol (CeP) and Remifentanil (CeR) during Total Intravenous Anesthesia with Target Controlled Infusion (TIVA-TCI).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Undergo general anaesthesia with Targeted Controlled Infusion of Propofol (Eleveld or Schnider model) and Remifentanil (Minto model) and CONOX monitoring

Exclusion criteria

* Neurological disease * Psychiatric disease * Obesity * Locoregional anesthesia

Design outcomes

Primary

Measure	Time frame	Description
Correlation between qCON and qNOX	CONOX values will be recorded from start of anesthesia to the return of responsiveness at the end of surgery	qCON and qNOX values from CONOX monitor will be compared

Secondary

Measure	Time frame	Description
Correlation between qCON and concentrations of Propofol(CeP)	CONOX and TCI values will be recorded from start of anesthesia to the return of responsiveness at the end of surgery	qCON and CeP values from CONOX monitor and infusion pump will be compared
Correlation between qNOX and concentrations of Remifentanil (CeR)	CONOX and TCI values will be recorded from start of anesthesia to the return of responsiveness at the end of surgery	qNOX and CeR values from CONOX monitor and infusion pump will be compared

Countries

Italy

Contacts

Primary ContactFederico Linassi, MD

federico.linassi@gmail.com0422322440

Outcome results