Mandibular Fractures
Conditions
Brief summary
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
Interventions
PROCEDUREOpen Reduction & Internal Fixation
Open Reduction & Internal Fixation of Mandibular fracture either through intraoral or extraoral approaches.
Sponsors
Aya Ayman Ahmed
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Single mandibular fracture. * ORIF is done by two plates fixation with titanium plates and screws. * Age (18-50 years). * Recent fracture (less than 2 weeks).
Exclusion criteria
* Pathological fractures. * Medical compromised patient. * Presence of concomitant injuries. * Patients receive radiotherapy. * Patients receive blood transfusion.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| IL-17 | 6- weeks | Interleukin-17 |
| OPG | 6- weeks | Osteoprotegerin |
Secondary
| Measure | Time frame |
|---|---|
| Blood Loss | in operation room |
| Operative time | Operative time in minutes |
Outcome results
None listed