Diaphragm
Conditions
Brief summary
* Assessment of diaphragmatic function (excursion, thickness variation, thickness ratio) in COPD and bronchial asthma patients. * Assessment of presence of correlation between diaphragmatic dysfunction and pulmonary function. * Assessment of possible association between diaphragmatic dysfunction and presence of reversibility in pulmonary function post bronchodilator.
Detailed description
* Assessment of diaphragmatic function (excursion, thickness variation, thickness ratio) in COPD and bronchial asthma patients. * Assessment of presence of correlation between diaphragmatic dysfunction and pulmonary function (FEV1/FVC). * Assessment of possible association between diaphragmatic dysfunction and presence of reversibility in pulmonary function post bronchodilator (short acting B2 agonist)
Interventions
DEVICEultrasound
5\. Transthoracic ultrasound for both right and left diaphragm during inspiration and expiration.
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Stable patients (not in exacerbation).
Exclusion criteria
* Patients with comorbidities as cardiac, renal or hepatic diseases. * Patients who have combined COPD and bronchial asthma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| diaphragmatic function | 2 years | Compare diaphragmatic function using ultrasound device by measuring diaphragmatic thickness in both stable COPD and bronchial asthma patients. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| pulmonary function . | 2 years | assess the degree of effect of diaphragmatic dysfunction on pulmonary function measured by spirometry FEV1/FVC (forced expiratory volume1/ forced Vidal capacity ) |
Outcome results
None listed